Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

20 May 2010

Comparison of efficacy of MR sequences used for detection of focal liver lesions

Andrzej Cieszanowski, Agnieszka Grodzicka, Edyta Maj, Barbara Gornicka, Kaczynski Bartosz, Mariusz Grodzicki, Marek Krawczyk, Olgierd Rowinski

Med Sci Monit 2010; 16(1): 66-74 :: ID: 880586

Abstract

Background: The purpose of this study was to compare the sensitivities of different MR sequences (T2 TSE, DW EPI, T1 SGE) in detection of focal hepatic lesions.
Material/Methods: Evaluation included the MR studies (1.5T Unit: Magnetom Avanto) of 81 patients. Pathologic verification was obtained in 29 patients, whereas in remaining 52 patients, final diagnosis was based on other imaging studies, follow-up, and clinical data. In 56 patients, 171 liver lesions were confirmed: 84 malignant (52 metastases, 20 HCCs, 9 hemangioendotheliomas, 2 CCAs, 1 cystadenocarcinoma), and 87 benign (35 cysts, 31 hemangiomas, 13 abscesses, 7 FNHs, 1 cystadenoma). In 25 patients, liver lesions were excluded. Two radiologists identified the number of lesions on images obtained with the use of following sequences: T2WTSE, T2W fat-sat TSE, DW EPI (b=50,400,800 s/mm2), chemical shift T1 SGE (In-Out SGE), 3D T1 spoiled gradient-echo 3DT1SGE, dynamic 3DT1SGE post-Gd-BOPTA injection (with arterial, portal venous, parenchymal, 5 min-delayed phases) and 3DT1SGE 60-90 min post-Gd-BOPTA.
Results: Applied MR techniques yielded following sensitivities for detection of focal hepatic lesions: T2TSE 78.9%, T2 fat-sat 89.5%, DW EPI 95.9%, chemical shift T1SGE 80.7%, 3DT1SGE 81.9%, 3DT1SGE in arterial phase 93.0%, in portal venous phase 92.4%, in parenchymal phase 87.7%, in delayed phase 87.1%, and in hepatobiliary phase (60–90 min post-Gd-BOPTA) 84.8%.
Conclusions: The highest number of focal hepatic lesions was visualized on DW EPI sequence (n=164, sensitivity – 95.9%), followed by 3DT1SGE in arterial phase (n=159, sensitivity – 93.0%), 3DT1SGE in portal venous phase (n=158, sensitivity – 92.4%), and T2TSE fat-sat sequence (n=153, sensitivity – 89.5%).

Keywords: Magnetic Resonance Imaging, Liver Neoplasms, Contrast Media, Gadobenate dimeglumine

0 Comments

Editorial

01 February 2023 : Editorial  

Editorial: The XBB.1.5 (‘Kraken’) Subvariant of Omicron SARS-CoV-2 and its Rapid Global Spread

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.939580

Med Sci Monit 2023; 29:e939580

SARS-CoV-2/COVID-19

19 January 2023 : Clinical Research  

Evaluation of Health-Related Quality of Life and Mental Health in 729 Medical Students in Indonesia During ...

Med Sci Monit In Press; DOI: 10.12659/MSM.938892  

27 December 2022 : Clinical Research  

Effect of Physiotherapy to Correct Rounded Shoulder Posture in 30 Patients During the COVID-19 Pandemic in ...

Med Sci Monit 2022; 28:e938926

10 December 2022 : Clinical Research  

Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warn...

Med Sci Monit 2022; 28:e938647

In Press

03 Feb 2023 : Clinical Research  

Treatment of Gingival Recession Defects with Pouch and Tunnel Technique Using Connective Tissue Graft and L...

Med Sci Monit In Press; DOI: 10.12659/MSM.938865  

02 Feb 2023 : Clinical Research  

Online Questionnaire-Based Study to Evaluate the Attitudes and Use of Rubber Dental Dams by Saudi Dental Pr...

Med Sci Monit In Press; DOI: 10.12659/MSM.938672  

02 Feb 2023 : Database Analysis  

Prognostic-Related Biomarkers in Pancreatic Ductal Adenocarcinoma Correlating with Immune Infiltrates Based...

Med Sci Monit In Press; DOI: 10.12659/MSM.938785  

01 Feb 2023 : Clinical Research  

Comparison of 3 Enzyme-Linked Immunoassay Methods to Evaluate Serum Concentrations of Infliximab and Antibo...

Med Sci Monit In Press; DOI: 10.12659/MSM.939084  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750