Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

20 May 2010

Lateral rectus muscle as a new reference point in estimation of Graves’ ophthalmopathy activity

Agata Majos, Michał Pająk, Marcin Elgalal, Marek Olszycki, Ludomir Stefańczyk

Med Sci Monit 2010; 16(1): 80-85 :: ID: 880588

Abstract

Background: The clinical progression of Grave’s ophthalmopathy (GO) is evaluated based on different parameters. Still, there is greater opportunity to carry out morphometric measurements, than to perform a quasi patho-physiological assessment.
The aims of this study were to evaluate the correlation of T2 relaxation time to muscle volume based on MR imaging and to investigate whether individual physical relativization of extraocular muscle volume significantly influences results.
Material/Methods: Ten controls and 20 patients underwent MR examination. Quantitative muscle assessment was carried out using a numerical segmentation image technique. T2 relaxation times were measured for each muscle, and a standardization algorithm was applied based on T2 relaxation time of ipsilateral frontal lobe white matter.
For each extraocular muscle, an absolute volume and a relative value were calculated by subtracting from each of these muscles’s volume from the volume of the lateral rectus muscle (RM) within the same orbital cavity.
Results: Highest correlation for relative T2 relaxation time and muscle volume was observed for inferior RM (value of r=0.520, which increased to r=0.660 after relativization). An increase in correlation for medial RM was also noted from r=0.473 to r=0.48. However, this correlation decreased slightly for superior RM from a value of r=0.597 to r=0.525.
Conclusions: Oculomotor muscle volume closely correlates to T2 relaxation time. Individual physical objectification significantly increases this correlation for MRM and IRM and consequently enables more precise use of muscle volume as an indicator of GO. Relativization is essential for data from both magnetic resonance and computer tomography studies.

Keywords: Graves’ ophthalmopathy, volume assessment, computer applications

0 Comments

Editorial

01 February 2023 : Editorial  

Editorial: The XBB.1.5 (‘Kraken’) Subvariant of Omicron SARS-CoV-2 and its Rapid Global Spread

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.939580

Med Sci Monit 2023; 29:e939580

SARS-CoV-2/COVID-19

19 January 2023 : Clinical Research  

Evaluation of Health-Related Quality of Life and Mental Health in 729 Medical Students in Indonesia During ...

Med Sci Monit In Press; DOI: 10.12659/MSM.938892  

27 December 2022 : Clinical Research  

Effect of Physiotherapy to Correct Rounded Shoulder Posture in 30 Patients During the COVID-19 Pandemic in ...

Med Sci Monit 2022; 28:e938926

10 December 2022 : Clinical Research  

Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warn...

Med Sci Monit 2022; 28:e938647

In Press

03 Feb 2023 : Clinical Research  

Treatment of Gingival Recession Defects with Pouch and Tunnel Technique Using Connective Tissue Graft and L...

Med Sci Monit In Press; DOI: 10.12659/MSM.938865  

02 Feb 2023 : Clinical Research  

Online Questionnaire-Based Study to Evaluate the Attitudes and Use of Rubber Dental Dams by Saudi Dental Pr...

Med Sci Monit In Press; DOI: 10.12659/MSM.938672  

02 Feb 2023 : Database Analysis  

Prognostic-Related Biomarkers in Pancreatic Ductal Adenocarcinoma Correlating with Immune Infiltrates Based...

Med Sci Monit In Press; DOI: 10.12659/MSM.938785  

01 Feb 2023 : Clinical Research  

Comparison of 3 Enzyme-Linked Immunoassay Methods to Evaluate Serum Concentrations of Infliximab and Antibo...

Med Sci Monit In Press; DOI: 10.12659/MSM.939084  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750