Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

20 May 2010

Lateral rectus muscle as a new reference point in estimation of Graves’ ophthalmopathy activity

Agata Majos, Michał Pająk, Marcin Elgalal, Marek Olszycki, Ludomir Stefańczyk

Med Sci Monit 2010; 16(1): 80-85 :: ID: 880588

Abstract

Background: The clinical progression of Grave’s ophthalmopathy (GO) is evaluated based on different parameters. Still, there is greater opportunity to carry out morphometric measurements, than to perform a quasi patho-physiological assessment.
The aims of this study were to evaluate the correlation of T2 relaxation time to muscle volume based on MR imaging and to investigate whether individual physical relativization of extraocular muscle volume significantly influences results.
Material/Methods: Ten controls and 20 patients underwent MR examination. Quantitative muscle assessment was carried out using a numerical segmentation image technique. T2 relaxation times were measured for each muscle, and a standardization algorithm was applied based on T2 relaxation time of ipsilateral frontal lobe white matter.
For each extraocular muscle, an absolute volume and a relative value were calculated by subtracting from each of these muscles’s volume from the volume of the lateral rectus muscle (RM) within the same orbital cavity.
Results: Highest correlation for relative T2 relaxation time and muscle volume was observed for inferior RM (value of r=0.520, which increased to r=0.660 after relativization). An increase in correlation for medial RM was also noted from r=0.473 to r=0.48. However, this correlation decreased slightly for superior RM from a value of r=0.597 to r=0.525.
Conclusions: Oculomotor muscle volume closely correlates to T2 relaxation time. Individual physical objectification significantly increases this correlation for MRM and IRM and consequently enables more precise use of muscle volume as an indicator of GO. Relativization is essential for data from both magnetic resonance and computer tomography studies.

Keywords: Graves’ ophthalmopathy, volume assessment, computer applications

0 Comments

Editorial

15 August 2022 : Editorial  

Editorial: The Metabolic (Dysfunction) Associated Fatty Liver Disease (MAFLD)-Non-Alcoholic Fatty Liver Disease (NAFLD) Debate: A Forced Consensus and The Risk of a World Divide

Nahum Méndez-Sánchez, Ming-Hua Zheng, Takumi Kawaguchi, Shiv K. Sarin
Liver Research Unit, Medica Sur Clinic & Foundation and Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

DOI: 10.12659/MSM.938080

Med Sci Monit 2022; 28:e938080

In Press

12 Aug 2022 : Clinical Research  

Risk Factors and Pathogen Spectrum in Continuous Ambulatory Peritoneal Dialysis-Associated Peritonitis: A S...

Med Sci Monit In Press; DOI: 10.12659/MSM.937112  

11 Aug 2022 : Meta-Analysis  

Optimal Surgical Treatment Method for Anterior Cruciate Ligament Rupture: Results from a Network Meta-Analysis

Med Sci Monit In Press; DOI: 10.12659/MSM.937118  

10 Aug 2022 : Review article  

Programmed Cell Death in Diabetic Nephropathy: A Review of Apoptosis, Autophagy, and Necroptosis

Med Sci Monit In Press; DOI: 10.12659/MSM.937766  

10 Aug 2022 : Database Analysis  

Use and Effects of Augmentation of Labor with Oxytocin: A Single-Center, Retrospective, Case-Control Study ...

Med Sci Monit In Press; DOI: 10.12659/MSM.937557  

Most Viewed Current Articles

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750