Abstract

Background: To investigate the prevalence of moderate or severe chronic kidney disease in patients with severe versus mild or moderate peripheral arterial disease.
Material/Methods: We investigated the prevalence of moderate or severe chronic kidney disease diagnosed as an estimated glomerular filtration rate <60 ml/min/1.73 m2 in 130 patients with severe peripheral arterial disease (ankle-brachial index <0.60) and in 192 patients with mild or moderate peripheral arterial disease (ankle-brachial index 0.60-0.89) seen in a vascular surgery outpatient clinic.
Results: An estimated glomerular filtration rate of <30 ml/min/1.73 m2 was present in 51 of 322 patients (16%) with peripheral arterial disease, of 30–59 ml/min/1.73 m2 was present in 172 of 322 patients (53%) with peripheral arterial disease, and of ≥60 ml/min/1.73 m2 was present in 99 of 322 patients (31%) with peripheral arterial disease. An estimated glomerular filtration rate <60 ml/min/1.73 m2 was present in 105 of 130 patients (81%) with an ankle-brachial index <0.60 and in 118 of 192 patients (61%) with an ankle-brachial index of 0.60–0.89 (p<0.001).
Conclusions: The prevalence of moderate or severe chronic kidney disease is high in patients with peripheral arterial disease and is significantly higher (p<0.001) in patients with severe peripheral arterial disease than in patients with mild or moderate peripheral arterial disease.

Keywords: Peripheral Arterial Disease - physiopathology, New York - epidemiology, Glomerular Filtration Rate - physiology, Aged, 80 and over, Prevalence, Renal Insufficiency, Chronic - physiopathology