27 October 2018 : Clinical Research
Validity of Nottingham Hip Fracture Score in Different Health Systems and a New Modified Version Validated to the Greek PopulationKonstantinos Tilkeridis1ABE, Athanasios Ververidis1CDE, Georgios Kiziridis1BEF*, Dimitrios Kotzamitelos1BC, Dimitrios Galiatsatos2CD, Rodion Mavropoulos1B, Katerina Vlastimil Rechova3D, Georgios Drosos1AE
Med Sci Monit 2018; 24: CLR7665-7672
BACKGROUND: The Nottingham Hip Fracture Score (NHFS) is validated as a predictive mortality tool in patients with hip fracture. However, it has not been modified or validated widely other than in the UK NHS health systems.
MATERIAL AND METHODS: We assessed the predictive capability of the NHFS for 30-day mortality after surgery for hip fracture in the Greek population and then compared the original model to a modified one. We applied the NHFS to the Greek population and created a modified model of the NHFS by including the New Mobility Score (NMS) (Parker and Palmer, 1993) to the evaluated parameters and excluding the parameter of institution. We ran a prospective study over a period of 3 years in our institution, collecting full data from 349 patients. All data were analyzed using SPSS, version 20.
RESULTS: From all 349 patients, with a mean age of 80.82 years, only 85 (24.4%) were men. All patients were followed up for at least 30 days and the NHFS and modified NHFS prediction were compared with the mortality rate of patients. The area under the ROC curve for both models suggested acceptable accuracy (original NHFS 0.83, modified NHFS 0.84). Calibration was acceptable for both models (Hosmer-Lemeshow p=0.31 and 0.11, respectively).
CONCLUSIONS: Both the original and the modified NHFS were significant predictors of 30-day mortality. A higher-power study might be able to show superiority of the modified one for the Greek population in the future.
Keywords: Decision Support Techniques, Hip Fractures, Risk Factors, Validation Studies
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