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26 June 2019 : Clinical Research  

A New Approach for Root Surface Biomodification Using Injectable Platelet-Rich Fibrin (I-PRF)

Bozan Serhat İzol1EFG, Devrim Deniz Üner2ABDE*

DOI: 10.12659/MSM.915142

Med Sci Monit 2019; 25:4744-4750


BACKGROUND: This study investigated the potential effects of Injectable Platelet-Rich Fibrin (I-PRF) on root coverage of free gingival graft surgery.

MATERIAL AND METHODS: A total of 40 patients with Miller class I or II gingival recession were included. The patients who participated in this study were randomly divided into 2 groups, including the control and experiment groups. The patients in the control group were treated only with free gingival graft (FGG). The patients in the experiment group were treated with free gingival graft and injected with I-PRF as a root surface biomodification agent (FGG+I-PRF). The patients were called back after 3 months, and the amount of exposed root surface was determined and compared to the preoperative findings.

RESULTS: The mean initial exposed root surface was 4.7±1.49 mm for the FGG+I-PRF group, 4.1±1.07 mm for the FGG group, and 4.4±1.31 mm for all subjects. Three months after the operation, the mean root surface coverage values of the 2 groups were 3.5±1.05 and 3.9±0.78 mm in the control and experiment groups, respectively.

CONCLUSIONS: The findings showed that the injection of Injectable Platelet-Rich Fibrin (I-PRF) had a positive effect on root coverage in free gingival graft surgery.

Keywords: Gingiva, Immunologic Factors, Periodontal Cyst, Fibrin Tissue Adhesive, gingival recession, Platelet-Rich Fibrin, Surgical Flaps, Tooth Root, Treatment Outcome



12 September 2022 : Editorial  

Editorial: Treatment with Dual Incretin Receptor Agonists to Maintain Normal Glucose Levels May Also Maintain Normal Weight and Control Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)

Ana Luisa Ordóñez-Vázquez, Sofía Murúa Beltrán-Gall, Shreya C. Pal, Nahum Méndez-Sánchez
Liver Research Unit, Medica Sur Clinic Foundation, Mexico City, Mexico

DOI: 10.12659/MSM.938365

Med Sci Monit 2022; 28:e938365


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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750