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02 November 2019 : Clinical Research  

Skin Prick Testing to Identify Food Allergens in 8393 Children and Adolescents with Asthma in Chongqing, Southwest China

Rong Guo12ADEF, Ling Wang12BD, Xiao-Ping Yuan12CE*, Ping Sun23CD

DOI: 10.12659/MSM.915481

Med Sci Monit 2019; 25:8221-8229


BACKGROUND: The prevalence of food allergies in asthmatic children and adolescents has significantly increased over recent years. Nevertheless, the relevant clinical analyses are still lacking in China. Therefore, the present study aimed to determine common food allergens in pediatric patients with asthma in Chongqing, Southwest China.

MATERIAL AND METHODS: A total of 8393 asthmatic patients from Children’s Hospital of Chongqing Medical University (CHCMU) were enrolled in this retrospective study between October 2014 and July 2017. All patients underwent skin prick test (SPT) with 10 food allergens and recorded history of clinical reactivity. The correlations among the positive rates, categories of allergens, gender, age, and living environment were analyzed.

RESULTS: A total of 2544 patients (30.31%) had a positive SPT, while the prevalence of food allergy was 8%. Sea crab, peanut, and sea shrimp were the most common food allergens found in the studied population. The frequent food allergies were sea crab, peanuts, and sea shrimp.

CONCLUSIONS: Identifying allergens is important for the diagnosis and management of allergic disorders, and for performing immunotherapy.

Keywords: Asthma, Child, Food Hypersensitivity, Adolescent, Allergens, Child, Preschool, Infant, Prevalence, Skin Tests

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750