Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

26 June 2019 : Laboratory Research  

Influence of Deviated Centers of Rotation on Kinematics and Kinetics of a Lumbar Functional Spinal Unit: An In Vitro Study

Shengzheng Kuai1234ABEF, Xinyu Guan5CEF, Yang Li5BC, Weiqiang Liu5AG, Yunfeng Xu6CD, Wenyu Zhou23ADG*

DOI: 10.12659/MSM.915614

Med Sci Monit 2019; 25:4751-4758


BACKGROUND: Center of rotation (COR) has been used for assessing spinal motion quality. However, the biomechanical influence of COR deviation towards different directions during flexion-extension (FE) remains largely unknown. This study aimed to investigate the alteration in the range of motion (ROM), compressive force, shear force, and neutral zone size (NZ) in a lumbar functional spinal unit (FSU), caused by the deviated COR in different directions during FE.

MATERIAL AND METHODS: Twelve human cadaveric lumbar FSUs (6 for L2–L3, 6 for L4–L5) were tested in a 6-degree-of-freedom servo-hydraulic load frame. These FSUs were firstly applied a 7.5 Nm pure moment to perform FE to obtain their natural COR during FE. Subsequently, they were subjected to FE around 9 established deviated CORs with 6 Nm cyclical loading.

RESULTS: It was found that the ROM and NZ increased significantly when the COR moved from the superior plane to the inferior plane for the L2–L3 unit and when the COR located in the superior plane compared with the inferior plane for the L4–L5 unit. The compressive forces for both FSUs demonstrated significant changes caused by COR shift in the same horizontal plane, while the shear forces demonstrated significant changes caused by COR shift in the same vertical plane.

CONCLUSIONS: The ROM, NZ, and shear force of FSU are sensitive to the vertical COR shift, while the compressive force of FSU is highly sensitive to the horizontal COR shift. Additionally, the kinematics and kinetics of the L2–L3 unit are more sensitive to COR location than those of the L4–L5 unit.

Keywords: Biomechanical Phenomena, in vitro, Spine, Cadaver, Compressive Strength, Kinetics, Lumbar Vertebrae, Motion, Range of Motion, Articular, Rotation

Add Comment 0 Comments

821 13


01 December 2023 : Editorial  

Editorial: Outbreaks of Post-Pandemic Childhood Pneumonia and the Re-Emergence of Endemic Respiratory Infections

Dinah V. Parums

DOI: 10.12659/MSM.943312

Med Sci Monit 2023; 29:e943312


In Press

04 Dec 2023 : Animal Research  

Effects of Intrathecal Ketamine on Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor and Mech...

Med Sci Monit In Press; DOI:  

01 Dec 2023 : Clinical Research  

Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St...

Med Sci Monit In Press; DOI:  

30 Nov 2023 : Review article  

Decoding the Neurological Sequelae of General Anesthesia: A Review

Med Sci Monit In Press; DOI:  

30 Nov 2023 : Clinical Research  

Enhanced Pain Relief and Muscle Growth in Individuals with Low Back Instability: The Impact of Blood Flow R...

Med Sci Monit In Press; DOI:  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750