Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

04 June 2019 : Clinical Research  

Biomechanical Effect of Different Graft Heights on Adjacent Segment and Graft Segment Following C4/C5 Anterior Cervical Discectomy and Fusion: A Finite Element Analysis

Yuhua Zhang123BCEF, Jiaming Zhou1BCEF, Xing Guo1BCEF, Zongxi Cai2DF, Haofei Liu2AD, Yuan Xue1ADG*

DOI: 10.12659/MSM.916629

Med Sci Monit 2019; 25:4169-4175


BACKGROUND: The finite element analysis (FEA) was used to explore the effect of different graft heights on adjacent segment and graft segment stress after C4/5 anterior cervical discectomy and fusion (ACDF).

MATERIAL AND METHODS: A detailed, geometrically accurate 3-dimensional cervical spine model was successfully built from computed tomography (CT) scanning of a healthy adult male. We changed the graft height in C4–C5 to be 90%, 150%, 175%, and 200% of the preoperative disc height and simulated the postoperative scenarios with different bone graft height, respectively. A stress analysis was conducted on the adjacent segment and graft segment.

RESULTS: The maximum von Mises stress on C3–C4 showed that when the graft height was 200%, the values were 0.99 MPa, 0.85 MPa, 0.91 MPa, and 0.89 MPa in different loading conditions. For C5–C6, the maximum von Mises stress was 0.77 MPa, 0.83 MPa, 0.91 MPa, and 0.81 MPa, observed when the graft height was 175%, except in extension condition. With regard to graft segment (C4–C5), the biggest von Mises stress was 1.25 MPa, 1.77 MPa, 1.75 MPa, and 1.81 MPa observed at 200% graft height. For these 3 segments, the smallest von Mises stress was found at 150% graft height under the 4 loading conditions.

CONCLUSIONS: The graft height makes an important difference on the stress on the adjacent segment and the graft segment after anterior cervical discectomy and fusion. A 150% graft height was considered the proper graft height in C4/C5 ACDF, with the lowest stress on the adjacent segment and the graft segment.

Keywords: Biomechanical Phenomena, Finite Element Analysis, intervertebral disc, Spinal Fusion, Bone Transplantation, Cervical Vertebrae, Computer Simulation, Diskectomy, intervertebral disc degeneration, Range of Motion, Articular, Tomography, X-Ray Computed, Weight-Bearing

Add Comment 0 Comments

868 14


01 May 2023 : Editorial  

Editorial: Twenty Years On from Sequencing the Human Genome, Personalized/Precision Oncology Prepares to Meet the Challenges of Checkpoint Inhibitor Therapy

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.940911

Med Sci Monit 2023; 29:e940911


In Press

31 May 2023 : Review article  

Prevalence, Diagnosis, and Management of Eclampsia and the Need for Improved Maternal Care: A Review

Med Sci Monit In Press; DOI: 10.12659/MSM.939919  

30 May 2023 : Clinical Research  

A Case-Control Study of Cognitive Function in Patients with End-Stage Renal Disease Before and After Hemodi...

Med Sci Monit In Press; DOI: 10.12659/MSM.940409  

30 May 2023 : Review article  

A Review of the Role of the Zebrafish (Danio reiro) in Preclinical and Clinical Models of Biomarker Identif...

Med Sci Monit In Press; DOI: 10.12659/MSM.940550  

30 May 2023 : Database Analysis  

The COVID-19 Crisis and the Incidence of Alcohol-Related Deaths in Poland

Med Sci Monit In Press; DOI: 10.12659/MSM.940904  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750