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29 May 2019 : Clinical Research  

Efficacy of Total Aortic Arch Replacement Combined with Frozen Elephant Trunk in Aortic Reoperation

Guanglong Sun1ABE, Lizhong Sun2ADG*, Junming Zhu2CF, Yongmin Liu2BE, Yipeng Ge2AD, Shijun Xu2BD

DOI: 10.12659/MSM.916938

Med Sci Monit 2019; 25:3998-4004

Abstract

BACKGROUND: The aim of this study was to estimate the long-term efficacy of total aortic arch replacement combined with the frozen elephant trunk (TAR+FET) technique for aortic disease following a prior cardiac surgery procedure.

MATERIAL AND METHODS: We performed TAR+FET for 118 patients for major vessel disease following a prior cardiac procedure with median sternotomy incision. All patients were divided into 5 groups: in group A, the prior major procedure was aortic valve replacement (AVR); in group B, the prior major procedure was isolated ascending aorta replacement; in group C, the prior major procedure was aortic root replacement; in group D, the prior major procedure was aortic arch replacement or intervention; and in group E, the prior major procedure was ‘other’ cardiac operative procedure. The long-term follow-up visit results were estimated using the Kaplan-Meier method.

RESULTS: The 30-day mortality rate after the operation was 13.6% (16/118) – 2 died in group A, 1 in group B, 8 in group C, 4 in group D, and 1 in group E. Follow-up visits were completed in 99% of patients. The mean follow-up time was 47.6±36.3 months and 12 patients had died by follow-up, so the total long-term survival rate was 76.3%. One-year survival rates of the 5 groups were 85% (group A), 93.8% (group B), 82.3% (group C), 50% (group D), and 50% (group E), respectively. Five-year survival rates of the 5 groups were 85%, 93.8%, 80.6%, 50%, and 50%, respectively.

CONCLUSIONS: The TAR+FET technique is feasible and efficacious for aortic reoperation in patients who previously underwent cardiac surgery since the short-term mortality in patients with recurrent aortic arch disease after cardiac surgery is not high.

Keywords: Aortic Diseases, Reoperation, Treatment Outcome, Aged, Aneurysm, Dissecting, Aorta, Thoracic, Blood Vessel Prosthesis, Blood Vessel Prosthesis Implantation, Cardiac Surgical Procedures, Follow-Up Studies, Hospital Mortality, Kaplan-Meier Estimate, Middle Aged, Postoperative Complications, Retrospective Studies

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750