Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

29 November 2019 : Clinical Research  

Computed Tomography Perfusion Imaging Quality Affected by Different Input Arteries in Patients of Internal Carotid Artery Stenosis

Xugao Chen1BC, Jianxun Zou1DE, Lijuan Bao1CF, Jinge Hu2BC, Guowei Ye1AG*

DOI: 10.12659/MSM.917995

Med Sci Monit 2019; 25:9067-9072

Abstract

BACKGROUND: The aim of this study was to explore the influence of different input arteries on the parameters of computed tomography (CT) perfusion imaging for patients with different degree of stenosis of internal carotid artery (ICA).

MATERIAL AND METHODS: Forty patients were enrolled in the present study and divided into mild, moderate, severe stenosis and occlusion groups respectively with each 10 patients in each group. In reconstruction of cerebral CT perfusion (CTP) images, each raw perfusion image was reconstructed 3 times based on different reference input artery, including bilateral middle cerebral artery (MCA) and basilar arteries (BA). Region of interest (ROI) was drawn in the central territories of bilateral anterior cerebral artery, middle cerebral artery and posterior cerebral artery. And regional cerebral blood flow (rCBF) regional cerebral blood volume (rCBV), mean transit time (MTT), time to peak (TTP) and delay time (DT) were obtained from those ROI corresponding perfusion images.

RESULTS: In patients with mild and moderate ICA stenosis, there was no significant difference of perfusion parameters based on different input arteries (P>0.05). However, in severe ICA stenosis and occlusion CBF, MTT, and DT were significant different in affect side of the MCA group compared to the others (P<0.05).

CONCLUSIONS: Large intracranial artery can be selected as the input artery for patients with mild to moderate ICA stenosis, while for patients with severe stenosis and occlusion of ICA, the contra lateral middle cerebral artery or basilar artery would be better choice.

Keywords: carotid stenosis, Diagnosis, Tomography Scanners, X-Ray Computed, Carotid Artery, Internal, Cerebrovascular Circulation, Middle Cerebral Artery, Perfusion, perfusion imaging, Tomography, X-Ray Computed

Add Comment 0 Comments

Editorial

01 May 2024 : Editorial  

Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)

Dinah V. Parums

DOI: 10.12659/MSM.944927

Med Sci Monit 2024; 30:e944927

In Press

07 May 2024 : Clinical Research  

Treatment of AVN-Induced Proximal Pole Scaphoid Nonunion Using a Fifth and Fourth Extensor Compartmental Ar...

Med Sci Monit In Press; DOI: 10.12659/MSM.944553  

16 Mar 2024 : Clinical Research  

Diagnostic Efficiency of ACR-TIRADS Score for Differentiating Benign and Malignant Thyroid Nodules of Vario...

Med Sci Monit In Press; DOI: 10.12659/MSM.943228  

08 May 2024 : Clinical Research  

Effect of Individualized PEEP Guided by Driving Pressure on Diaphragm Function in Patients Undergoing Lapar...

Med Sci Monit In Press; DOI: 10.12659/MSM.944022  

21 Mar 2024 : Clinical Research  

Impact of Serum Vitamin D, B6, and B12 and Cognitive Functions on Quality of Life in Peri- and Postmenopaus...

Med Sci Monit In Press; DOI: 10.12659/MSM.943249  

Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750