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07 May 2026 : Clinical Research  

[In Press] Body Weight and Insulin Resistance Indicators Among Children

Monika Gesek ORCID logo1ABCDEFG, Danuta Zarzycka ORCID logo1ACDFG, Arkadiusz Jędrzejewski ORCID logo1ABCD, Marzena Szczygielska1ABCD, Renata Widera1ABCD, Monika Wójtowicz-Marzec ORCID logo1ACDF

DOI: 10.12659/MSM.951434

Med Sci Monit In Press; DOI: 10.12659/MSM.951434  

Available online: 2026-05-07, In Press, Corrected Proof

Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule

Abstract

BACKGROUND
A child’s body weight is one of the factors that can contribute to the development of insulin resistance. The aim of the study was to determine the relationship between body weight and selected indicators of insulin resistance in children.
MATERIAL AND METHODS
A cross-sectional study was conducted at the University Children’s Hospital in Lublin between 2023 and 2024, involving a group of 99 children aged 8 to 14 years. Anthropometric measurements (body weight and height) were taken, clinical data (sex, age, BMI, classification of obesity), and biochemical indicators (glucose and insulin levels) were analyzed. Insulin resistance was identified using the Homeostatic Model Assessment of Insulin Resistance index and the Quantitative Insulin Sensitivity Check Index.
RESULTS
Insulin resistance was diagnosed in 43.43% of children. Mean insulin values were higher in girls (15.99; median, 12.10) than in boys (11.02; median, 7.86). Individuals with insulin resistance had a higher body mass index (P=0.001), and insulin resistance was more common in children with overweight than in those with normal weight or low weight.
CONCLUSIONS
These results confirm that many children and adolescents with overweight have insulin resistance. This condition is associated with an increased risk of developing metabolic disorders and may lead to serious long-term health consequences. An early diagnosis allows the implementation of preventive measures, particularly lifestyle modifications, to reduce the progression of metabolic abnormalities.

Keywords: Body Mass Index; Body Weight; Child; Insulin Resistance

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DOI: 10.12659/MSM.952454

Med Sci Monit 2026; 32:e952454

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750