01 May 2026 : Clinical Research
[In Press] Preventing Ventilator-Associated Pneumonia: A Multicenter Cross-Sectional Study of Knowledge, Attitudes, and Practices of Medical Staff in Chinese Hospitals
Chunhua Liu1ABCDEF, Zijie Sun2AEF, Yanran Li3AC, Chengjin Li1ACD, Fei Wang4CE, Yan Pan1B, Yuzhi Zhou1B, Fengzhu Chen5ADOI: 10.12659/MSM.952124
Med Sci Monit In Press; DOI: 10.12659/MSM.952124
Available online: 2026-05-01, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Ventilator-associated pneumonia (VAP) is a severe complication in mechanically ventilated patients. Understanding the knowledge, attitudes, and practices (KAP) of healthcare providers is crucial for prevention. This study aimed to assess the KAP regarding VAP among doctors and nurses in intensive care units (ICU) and respiratory departments across 9 hospitals in China.
MATERIAL AND METHODS
This multicenter cross-sectional study was conducted from April to June 2024 in 9 hospitals in China. A total of 224 participants, including 62 doctors and 162 nurses, completed a validated questionnaire in intensive care and respiratory departments. Statistical analyses included descriptive statistics, correlation, logistic regression, and structural equation modeling (SEM) for the nurse cohort.
RESULTS
A total of 224 valid questionnaires were collected, with 62 from doctors and 162 from nurses. The KAP scores were 9.88±1.42, 41.67±2.86, and 30.45±4.12 for doctors, and 34.45±4.59 for nurses. For nurses, there was a positive correlation between knowledge and attitudes (r=0.212, P=0.007). SEM showed that knowledge directly affected attitudes (β=6.45, P<0.001), but did not significantly predict practices.
CONCLUSIONS
Medical staff showed adequate knowledge, positive attitudes, and good practices regarding VAP. However, structural modeling revealed that knowledge and attitudes did not significantly predict practices, suggesting the need to explore other factors and for targeted interventions for better VAP prevention.
Keywords: Cross-Sectional Studies; Health Knowledge, Attitudes, Practice; Surveys and Questionnaires; Ventilator-Associated Pneumonia
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