04 July 2026 : Clinical Research
[In Press] Impact of Treatment Modality on Pain, Sexual Function, and Psychological Well-Being in Patients With Bartholin's Duct Cyst and Abscess: A Prospective Observational Cohort Study
Sertaç AyçiçekDOI: 10.12659/MSM.952422
Med Sci Monit In Press; DOI: 10.12659/MSM.952422
Available online: 2026-07-04, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Bartholin’s duct cyst and abscess are common benign vulvar conditions. Optimal treatment varies according to recurrence, pain, and patient-centered outcomes. Comparative evidence regarding Word catheter placement, silver nitrate, and marsupialization is limited.
MATERIAL AND METHODS
This prospective observational cohort study included 111 women diagnosed with Bartholin’s duct cyst or abscess between December 2020 and May 2021. Patients underwent treatment according to clinical practice, physician preference, and patient choice. Pain intensity (primary outcome), sexual function, and psychological status were evaluated using the Visual Analog Scale (VAS), Female Sexual Function Index (FSFI), and Hospital Anxiety and Depression Scale (HADS), respectively. Recurrence and postoperative analgesic requirements were also evaluated. Assessments were performed before treatment and on postoperative day 1, week 1, and month 1.
RESULTS
All treatment modalities were associated with significant reductions in pain intensity according to the VAS (all P<0.001). In the Word catheter group, significant changes were observed in VAS (P<0.001), HADS-anxiety (P<0.001), and FSFI (P=0.044) scores. In the silver nitrate group, significant improvements were observed in VAS (P<0.001) and HADS-anxiety (P=0.026) scores; FSFI score alterations were not statistically significant (P=0.209). In the marsupialization group, significant improvement was observed in VAS scores (P<0.001); FSFI (P=0.412) and HADS-anxiety (P=0.236) score alterations were not statistically significant.
CONCLUSIONS
Word catheter placement, silver nitrate, and marsupialization had distinct effects on pain relief and psychological outcomes; sexual function outcomes were comparable. Treatment selection should consider patient-centered outcomes and clinical resolution.
Keywords: Anxiety; Bartholin's Cyst; Gynecology; Pain Measurement; Prospective Studies; Sexual Dysfunction, Physiological
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