12 May 2026 : Clinical Research
[In Press] Outcomes After Minimally Invasive Intramedullary Nail Fixation and Locking Plate Fixation Among Patients With Proximal Humerus Fractures
Zhikuan Wang1ABCDEF, Jinshi Liu1ABCDEF, Letian Zeng1BCDF, Dingwei Long1BCDF, Donggui Zeng1BCG, Lin Liu2ABCDEFGDOI: 10.12659/MSM.952670
Med Sci Monit In Press; DOI: 10.12659/MSM.952670
Available online: 2026-05-12, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Minimally invasive intramedullary nail (IMN) fixation has gained increasing attention for proximal humerus fractures. We compared operative time, intraoperative blood loss, postoperative pain, and functional outcomes between minimally invasive IMN fixation and locking plate fixation.
MATERIAL AND METHODS
This prospective study enrolled 61 patients from January 2019 to January 2024: 36 treated via IMN (Group A) and 25 treated via locking plates (Group B). Operative time, incision length, blood loss, visual analog scale (VAS) scores, complication rates, and postoperative shoulder function were analyzed.
RESULTS
Group A had a shorter operative time, smaller incision length, less blood loss (all P=0.001); shorter hospital stay (P=0.006); lower VAS scores (P=0.04); and fewer complications (P=0.03) than Group B. Group A demonstrated better shoulder flexion at 1, 3, and 6 months (P<0.001; =0.003, 0.029). At 1, 3, 6, and 12 months, Group A showed superior external rotation, internal rotation, and abduction versus Group B (all P<0.05). The neck-shaft angle was greater and loss of humeral head height was lower in Group A at 3, 6, and 12 months (all P<0.05). Constant-Murley scores were higher in Group A at 1 and 3 months (P=0.008, 0.032); DASH scores were lower in Group A at 3 and 12 months (P=0.002, 0.009).
CONCLUSIONS
IMN fixation for proximal humerus fractures offers shorter operative time, fewer complications, and improved postoperative shoulder function, indicating superior clinical efficacy relative to locking plate fixation.
Keywords: Fracture Fixation; Intramedullary Nailing; Minimally Invasive Surgical Procedures; Orthopedics; Proximal Humeral Fractures
Editorial
01 July 2026 : Editorial
Editorial: The WHO Identifies Ebola Disease Due to Bundibugyo Virus as a Public Health Emergency of International Concern (PHEIC) as Vaccine Development AcceleratesDOI: 10.12659/MSM.954627
Med Sci Monit 2026; 32:e954627
Most Viewed Current Articles
17 Jan 2024 : Review article 14,176,007
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
13 Nov 2021 : Clinical Research 3,757,384
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
14 Dec 2022 : Clinical Research 2,466,095
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research 708,748
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387






