25 April 2016 : Clinical Research
Determination of Serum Ceruloplasmin Concentration in Patients with Primary Open Angle Glaucoma with Cataract and Patients with Cataract Only: A Pilot Study
Monika Sarnat-KucharczykABCDEF, Wojciech RokickiABCDE, Jolanta Zalejska-FiolkaABDF, Dorota Pojda-WilczekABCEF, Ewa Mrukwa-KominekABCEGDOI: 10.12659/MSM.895352
Med Sci Monit 2016; 22:1384-1388
Abstract
BACKGROUND: The aim of this article was to describe the role of ceruloplasmin and to report preliminary results of ceruloplasmin concentrations in patients with primary open-angle glaucoma (POAG) with cataract and in patients with only cataract. Glaucoma, a neurodegenerative disease, is a heterogeneous group of conditions characterized by loss of retinal ganglion cells (RGC), their axons, progressive optic nerve damage, and visual field deterioration.
MATERIAL AND METHODS: The POAG group included 30 patients and the cataract group included 25 patients.
RESULTS: Ceruloplasmin plays an essential role in iron metabolism and inactivating free radicals. In the presented pilot study, serum ceruloplasmin level was lower in the POAG group in comparison to the group with only cataract.
CONCLUSIONS: In treating persistent inflammation in the course of glaucoma, antiglaucoma drugs may increase the permeability of the blood-ocular barrier, which may be connected with the lower concentration of serum ceruloplasmin in the glaucoma patients group.
Keywords: Cataract - complications, Ceruloplasmin - metabolism, Glaucoma, Open-Angle - complications, Pilot Projects
Editorial
01 March 2023 : Editorial
Editorial: Global Surveillance of Highly Pathogenic Avian Influenza Viruses in Poultry, Wild Birds, and Mammals to Prevent a Human Influenza PandemicDOI: 10.12659/MSM.939968
Med Sci Monit 2023; 29:e939968
SARS-CoV-2/COVID-19
03 March 2023 : Database Analysis
Reinfections from SARS-CoV-2: A Retrospective Study from the Gyncentrum Genetic Laboratory in Sosnowiec, Po...Med Sci Monit In Press; DOI: 10.12659/MSM.939452
09 February 2023 : Clinical Research
Evaluation of Health-Related Quality of Life and Mental Health in 729 Medical Students in Indonesia During ...Med Sci Monit 2023; 29:e938892
19 January 2023 : Clinical Research
Determining the Impact of the COVID-19 Pandemic on Dental Care in the Serbian Adult Population: An Online Q...Med Sci Monit 2023; 29:e939238
27 December 2022 : Clinical Research
Effect of Physiotherapy to Correct Rounded Shoulder Posture in 30 Patients During the COVID-19 Pandemic in ...Med Sci Monit 2022; 28:e938926
In Press
21 Mar 2023 : Clinical Research
Efficacy of Direct Anterior Approach Versus Posterior Lateral Approach for Total Hip Replacement in Patient...Med Sci Monit In Press; DOI: 10.12659/MSM.939682
21 Mar 2023 : Clinical Research
Intraoperative Hypotension and Its Association with Postoperative Acute Kidney Injury in Patients Undergoin...Med Sci Monit In Press; DOI: 10.12659/MSM.938945
20 Mar 2023 : Clinical Research
Management of Unstable C1 Fractures Involving the Lateral Mass: Posterior C1-C2 Screw-Rod Fixation and FusionMed Sci Monit In Press; DOI: 10.12659/MSM.938600
17 Mar 2023 : Clinical Research
Relationship Between Autonomic Nervous System Activity and Axial Length in ChildrenMed Sci Monit In Press; DOI: 10.12659/MSM.939451
Most Viewed Current Articles
13 Nov 2021 : Clinical Research
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical Research
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...DOI :10.12659/MSM.935379
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review article
A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...DOI :10.12659/MSM.936292
Med Sci Monit 2022; 28:e936292
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952