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14 August 2016 : Clinical Research  

Health-Related Quality of Life in HIV-Infected Men Who Have Sex with Men in China: A Cross-Sectional Study

Bo SongBCDEF, Cunling YanBCE, Yuanlong LinBCE, Fuxiang WangADE, Limei WangADE

DOI: 10.12659/MSM.897017

Med Sci Monit 2016; 22:2859-2870


BACKGROUND: China is undergoing a rapid growth in the human immunodeficiency virus (HIV) epidemic involving men who have sex with men (MSM). Reports about their health-related quality of life (HRQOL) are scarce. This study aimed to assess the HRQOL and factors influencing HIV-positive MSM in a city in the northeast of China.

MATERIAL AND METHODS: A cross-sectional study was conducted in Harbin city (Heilongjiang, China). HIV-positive MSM (n=125) were interviewed using the WHOQOL-HIV-BRIEF scale, the Berger HIV Stigma Scale, and other HIV-related questionnaires from June to August 2013.

RESULTS: Among the 6 dimensions of the HRQOL, HIV-related stigma was negatively associated with psychological (r=–0.316, P=0.0003) and spirituality domains (r=–0.324, P=0.0002). Physician support was positively associated with independence domain (r=0.393, P<0.0001). Hostile mentality was associated with psychological (r=0.479, P<0.0001) and spirituality domains (r=0.431, P<0.0001). Adverse effects of HAART were significantly correlated with physical (r=–0.542, P<0.0001) and psychological (r=–0.554, P<0.0001) domains. Multiple logistic regression showed that stigma (odds ratio (OR)=1.251, 95% confidence interval (95%CI): 1.088–1.439, P=0.002) and adverse effects of HAART (OR=1.117, 95%CI: 1.069–1.167, P<0.0001) were independent risk factors for low HRQOL. Physician support (OR=0.961, 95%CI: 0.941–0.982, P=0.0002) and CD4+ counts >350 (OR=0.033, 95%CI: 0.005–0.208, P=0.001) were independent protective factors in MSM receiving HAART. Hostile mentality (OR=0.936, 95%CI: 0.906–0.967, P<0.0001) was an independent protective factor of HRQOL in MSM not receiving HAART.

CONCLUSIONS: Psychological factors such as HIV-related stigma, hostile mentality, and physician support have a significant effect on HRQOL in MSM. These findings suggest specific psychological interventions to improve HRQOL in HIV-positive MSM in China.

Keywords: Cross-Sectional Studies, China - epidemiology, HIV Infections - psychology, Homosexuality, Male - statistics & numerical data, Odds Ratio, Quality of Life, Risk Factors, Surveys and Questionnaires

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750