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22 May 2026 : Clinical Research  

[In Press] Establishment of a Novel Approach for Drug Abuse Monitoring and Its Application in Medical Institutions

Kankan Qu1ABE, Zhongdong Zhang1F, Lujuan Cao2C, Lina Cao2D, Haohao Zhu1F, Zhenhe Zhou1G

DOI: 10.12659/MSM.952054

Med Sci Monit In Press; DOI: 10.12659/MSM.952054  

Available online: 2026-05-22, In Press, Corrected Proof

Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule

Abstract

BACKGROUND
Drug abuse is a global public health concern with substantial medical, psychological, and social consequences. Drug abuse monitoring (DAM) systems help identify patterns of substance misuse and support regulatory interventions. Current monitoring systems mainly rely on fixed-point reporting from addiction treatment centers, detention facilities, and compulsory detoxification institutions, which can lead to delayed detection and incomplete data coverage. Additionally, there is increasing misuse of prescription medications, over-the-counter drugs, and emerging psychoactive substances in medical settings. Therefore, establishment of a structured DAM approach within medical institutions is important to improve early detection and reporting of drug abuse.
MATERIAL AND METHODS
A single-center retrospective observational study was conducted at Wuxi Mental Health Centre to monitor patients diagnosed with drug/substance abuse between September 2020 and December 2024. A DAM research group was established to standardize reporting procedures, define staff responsibilities, and implement monitoring protocols linked to the national reporting system.
RESULTS
In total, 146 patients with drug/substance abuse were monitored: 41 male individuals (28.08%) and 105 female individuals (71.92%). Nineteen drugs or substances across 5 categories were identified. Sedative-hypnotic drugs represented the largest proportion of cases (98.63%). Antipyretic and analgesic drugs containing caffeine were abused in 4.11% of cases; dextromethorphan or Yumei tablets were involved in 3.42% of cases. Nitrous oxide abuse was identified in 2.05% of all monitored cases; affected patients were aged 17 to 25 years.
CONCLUSIONS
The proposed DAM approach was successfully implemented in a hospital setting and demonstrated feasibility for systematic monitoring of drug abuse in medical institutions.

Keywords: Drug Monitoring; Medical Institutions; Program Development; Standard Operating Procedures; Substance Abuse Detection; Psychoactive Drugs

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Dinah V. Parums ORCID logo

DOI: 10.12659/MSM.954627

Med Sci Monit 2026; 32:e954627

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750