22 May 2026 : Clinical Research
[In Press] Association Between Radiographic Knee Osteoarthritis, Pre-Fracture Mobility, and Hip Fracture Patterns in Older Adult Patients: A Retrospective Cohort Study
Süleyman Kaan ÖnerDOI: 10.12659/MSM.952678
Med Sci Monit In Press; DOI: 10.12659/MSM.952678
Available online: 2026-05-22, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Hip fracture morphology in older adults is influenced not only by bone mineral density but also by biomechanical and functional factors. Knee osteoarthritis (KOA) can alter lower-limb alignment, load distribution, and gait patterns, potentially affecting the type of hip fracture sustained. This study aimed to evaluate the association between radiographic KOA and hip fracture type while accounting for osteoporosis and pre-fracture mobility.
MATERIAL AND METHODS
This single-center retrospective cohort study included patients aged ≥65 years admitted with low-energy hip fractures between January 2018 and December 2023. Radiographic KOA was assessed using Kellgren-Lawrence classification, defined as grade ≥2. Osteoporosis was evaluated using dual-energy X-ray absorptiometry within 1 year before fracture. Pre-fracture mobility was assessed using the Parker Mobility Score, categorized as high (7-9), moderate (4-6), or low (0-3). Hip fractures were classified as femoral neck or intertrochanteric. Multivariable logistic regression identified predictors of intertrochanteric fracture.
RESULTS
Ninety-two patients (mean age 79.1±7.8 years; 67.4% female) were included. Intertrochanteric fractures occurred in 55 patients (59.8%). KOA was present in 56 patients (60.9%), and osteoporosis in 64 (69.6%). Intertrochanteric fractures were more common in patients with KOA (71.4% vs 41.7%, P=0.006). Low mobility was also associated with higher rates (79.4% vs 54.8% vs 40.7%, P=0.007). KOA (OR 2.87; 95% CI, 1.18-6.99; P=0.020) and low mobility (OR 3.41; 95% CI, 1.42-8.19; P=0.006) were independent predictors, whereas osteoporosis was not.
CONCLUSIONS
KOA and reduced mobility were found to be independently associated with intertrochanteric fracture patterns, underscoring the role of biomechanical and functional factors beyond bone density.
Keywords: Hip Fractures; Mobility Limitation; Orthopedics; Osteoporosis; Retrospective Studies
Editorial
01 July 2026 : Editorial
Editorial: The WHO Identifies Ebola Disease Due to Bundibugyo Virus as a Public Health Emergency of International Concern (PHEIC) as Vaccine Development AcceleratesDOI: 10.12659/MSM.954627
Med Sci Monit 2026; 32:e954627
In Press
Clinical Research
Effect of Low-Dose Vonoprazan on Hepatic Cytochrome P450 Activity By 13C-Aminopyrine Breath Test in Healthy...Med Sci Monit In Press; DOI: 10.12659/MSM.953332
Database Analysis
COVID-19 and Diabetes: Clinical Symptoms, Acute Kidney Injury, Inflammatory Response, and Poor Prognosis Fa...Med Sci Monit In Press; DOI: 10.12659/MSM.951864
Clinical Research
Comparative Effectiveness of a Nurse-Led Care Model vs Usual Care in Rheumatoid Arthritis: A Longitudinal C...Med Sci Monit In Press; DOI: 10.12659/MSM.953211
Clinical Research
Impact of Treatment Modality on Pain, Sexual Function, and Psychological Well-Being in Patients With Bartho...Med Sci Monit In Press; DOI: 10.12659/MSM.952422
Most Viewed Current Articles
17 Jan 2024 : Review article 14,176,007
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
13 Nov 2021 : Clinical Research 3,757,384
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
14 Dec 2022 : Clinical Research 2,466,095
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research 708,748
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387






