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01 July 2026 : Database Analysis  

[In Press] Accuracy, Self-Reported Confidence, and Overconfidence of Large Language Models in Endodontics: An Evaluation Using National Specialty Examination Questions

Mehmet Adıgüzel1ABCDEF

DOI: 10.12659/MSM.954052

Med Sci Monit In Press; DOI: 10.12659/MSM.954052  

Available online: 2026-07-01, In Press, Corrected Proof

Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule

Abstract

BACKGROUND
This study aimed to evaluate the accuracy, confidence, and overconfidence behavior of large language models (LLMs) in endodontics using questions derived from a national specialty entrance examination.
MATERIAL AND METHODS
A total of 123 text-based endodontic questions from the Turkish Dental Specialty Examination (2017-2026) were included after excluding annulled and image-based questions. Three LLMs (ChatGPT, Claude, and Gemini) were assessed. Each model answered all questions using a standardized prompt and provided a confidence score (0%-100%). Accuracy was recorded as correct/incorrect. Overconfidence was defined as incorrect responses with ≥90% confidence. Statistical analyses were performed using Cochran’s Q test, Friedman test, and post hoc pairwise comparisons with Bonferroni correction.
RESULTS
Accuracy rates were 89.4% for ChatGPT, 76.4% for Claude, and 90.2% for Gemini, with significant differences among models (χ²(2)=21.00, P<0.001). Confidence scores differed significantly (c2(2)=213.40, P<0.001), with Gemini demonstrating highest confidence (99.51±1.49), followed by ChatGPT (90.88±9.19) and Claude (80.22±11.10). Overconfidence rates were 9.8% for Gemini and 5.7% for ChatGPT, while no overconfident responses were observed for Claude (χ²(2)=14.53, P=0.001). Despite similar accuracy between ChatGPT and Gemini, confidence patterns differed markedly, demonstrating that comparable accuracy does not necessarily reflect comparable reliability.
CONCLUSIONS
LLMs demonstrated high accuracy in answering text-based endodontic examination questions; however, significant differences were observed in confidence behavior and overconfidence patterns. The presence of high-confidence incorrect responses suggests that accuracy alone may be insufficient to fully evaluate model reliability. These findings highlight the importance of considering confidence-related behavior alongside accuracy when assessing LLM performance in examination-style endodontic tasks.

Keywords: Large Language Models; Endodontics; Artificial Intelligence

Editorial

01 July 2026 : Editorial  

Editorial: The WHO Identifies Ebola Disease Due to Bundibugyo Virus as a Public Health Emergency of International Concern (PHEIC) as Vaccine Development Accelerates

Dinah V. Parums ORCID logo

DOI: 10.12659/MSM.954627

Med Sci Monit 2026; 32:e954627

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750