Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

25 June 2003

Talc powder vs doxycycline in the control of malignant pleural effusion: a prospective, randomized trial

Jarosław Kużdżał, Krzysztof Sładek, Dariusz Wąsowski, Jerzy Soja, Artur Szlubowski, Agnieszka Reifland, Marcin Zieliński, Andrzej Szczeklik

Med Sci Monit 2003; 9(6): PI54-59 :: ID: 12837

Abstract

Background:Various tubes have been advocated to deal with airway problems related to operative laryngoscopy. These include large- and small-diameter tubes localized in the supraglottic, subglottic, or transtracheal region.Material/Methods:We report our clinical experience with the use of the Benjet tube on 25 patients (23–64 years of age), American Society of Anesthesiologists physical status I and II, who underwent operative laryngoscopy. The Benjet tube was positioned within the trachea using a standard curved laryngoscope. Its proximal end was connected to a jet-ventilation system equipped with a pressure-limiting drive and airway-pressure gauge. A rigid microlaryngoscope was inserted, through which a sampling needle was introduced into the vicinity of the tracheal opening, for end-tidal carbon dioxide determination. Heart rate, non-invasive blood pressure, and hemoglobin oxygen saturation were continuously monitored.Results:The Benjet tube was found to be easy to introduce and remove and was unobtrusive in the larynx and trachea, allowing excellent surgical conditions. Cardiorespiratory parameters were stable and did not change from baseline values. End-tidal carbon dioxide values ranged between 34 and 35 mm Hg.Conclusions:We conclude that the Benjet tube is highly indicated for operative laryngoscopic procedures.Background:Malignant pleural effusion is a common problem in advanced cancers, contributing to the poor quality of life in this group of patients. The aim of the study was to assess the efficiency of talc powder and doxycycline in pleurodesis in patients with malignant pleural effusion in comparable conditions.Material/Methods:Of 52 patients screened, 33 entered the trial. They were randomized to the talc group (n=18) and the doxycycline group (n=15). Both groups were comparable with regard to age, sex and the most important variables influencing effectiveness of the procedure, i.e. primary malignancy and stage of metastatic involvement of the pleura. Efficiency of pleurodesis was prospectively assessed.Conclusions:Talc powder is superior to doxycycline in achieving pleurodesis in patients with malignant pleural effusion, in both short- and long-term observations.

Keywords: Anti-Bacterial Agents - therapeutic use, Breast Neoplasms - complications, Breast Neoplasms - parasitology, Doxycycline - therapeutic use, Lung Neoplasms - complications, Lung Neoplasms - pathology, Neoplasm Metastasis, Neoplasms, Unknown Primary - complications, Neoplasms, Unknown Primary - parasitology, Pleural Effusion, Malignant - prevention & control, Talc - therapeutic use

Add Comment 0 Comments

917 50

Editorial

01 November 2023 : Editorial  

Editorial: Factors Driving New Variants of SARS-CoV-2, Immune Escape, and Resistance to Antiviral Treatments as the End of the COVID-19 Pandemic is Declared

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville,

DOI: 10.12659/MSM.942960

Med Sci Monit 2023; 29:e942960

0:00

In Press

28 Nov 2023 : Clinical Research  

Impact of Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography on Therapeutic Decisions and ...

Med Sci Monit In Press; DOI: 10.12659/MSM.942122  

28 Nov 2023 : Clinical Research  

Long-Term Outcomes of Decompression and Grafting in Acute Pathological Proximal Femur Fractures in Children...

Med Sci Monit In Press; DOI: 10.12659/MSM.943031  

27 Nov 2023 : Clinical Research  

Comparison of Outcomes from Emergency Admissions to a Major Trauma Center in Turkey of 1646 Elderly Patient...

Med Sci Monit In Press; DOI: 10.12659/MSM.942916  

27 Nov 2023 : Clinical Research  

Evaluating Modified Ultrasound-Guided Serratus Anterior Plane Block for Enhanced Postoperative Recovery in ...

Med Sci Monit In Press; DOI: 10.12659/MSM.942757  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

0:00

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750