Background:Thyroglossal duct cysts are the most common congenital abnormality of thyroid development. They represent the most common midline neck masses in childhood, however, can be found in adults.Less than 1%of these cases are malignant.Our patient was a 28-yr-old man and his chief complaint was a progressively enlarged paramedian neck mass for a duration of 6 months.Case Report:We describe the imaging and pathologic characteristics of papillary carcinoma of thyroglossal duct cyst in a 28 years old man and subsequent treatment recommendations. The pathologic examination revealed papillary carcinoma of thyroglossal duct cyst followed by a total thyroidectomy.An axial CT scan of the neck showed a left Paramedian cyst,measuring 15x18 mm in the submental region.Neck dissection was done followed by 131I ablation.Conclusions:Base upon our past and current experience,we recommend that thyroglossal duct cyst with a microscopic focus of papillary carcinoma without cyst wall invasion be managed with Sistrunk procedurealong with effective suppressant dose of thyroxine.

Keywords: Carcinoma, Papillary - diagnosis, Carcinoma, Papillary - pathology, Carcinoma, Papillary - surgery, Thyroglossal Cyst - pathology, Thyroglossal Cyst - surgery