Background: The aim of our study was to evaluate the results of aparoscopic treatment in women with polycystic ovary syndrome, and to compare their response with ovulation, homocysteine levels, hormone profi les and clinical outcome before and after rilling.Material/Methods: We studied twenty-two nulliparous oligomenorrheic women with polycystic ovaries, complaining of infertility refractory to clomiphene-citrate treatment and subsequently underwent laparoscopic ovarian drilling (LOD) with a needle electrocautery. Endocrine assays, lipoproteins, homocysteine determinations and ultrasound evaluation were performed in all women before and after the procedure.Ovulatory and pregnancy rates and clinical outcome were assessed.Results: After the procedure, serum T, LH, homocysteine levels and LH-FSH ratio were signifi cantly lower than at baseline (0.93±0.15 vs 0.67±0.11 ng/ml, p

Keywords: Clomiphene - therapeutic use, Fertility Agents, Female - therapeutic use, Gynecologic Surgical Procedures - methods, Infertility, Female - drug therapy, Polycystic Ovary Syndrome - metabolism, Polycystic Ovary Syndrome - surgery, Cholesterol - metabolism, Clomiphene - therapeutic use, Fertility Agents, Female - therapeutic use, Gynecologic Surgical Procedures - methods, Homocysteine - metabolism, Hormones - metabolism, Infertility, Female - drug therapy, Laparoscopy - methods, Ovulation, Polycystic Ovary Syndrome - surgery, Pregnancy