Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

20 May 2003

Budd-Chiari syndrome – diagnosis and treatment

P. Małkowski, J. Pawlak, B. Michałowicz, R. Pacho, E. Leowska, T. Wróblewski, I. Gorzelak, M. Andrzejewska, J. Szczerbań, B. Górnicka, B. Wróblewska

Med Sci Monit 2003; 9(2): 41-47 :: ID: 15317

Abstract

The aim of the paper was to present the authors ’own experience in the field of diagnostics and treatment of Budd-Chiari syndrome.It is a retrospective analysis of 37 cases of Budd-Chiari syndrome treated in the Department since1980.Qualification for treatment was preceded with imaging diagnostics of the lifer and hepatic blood vessels,assessment of hepatic function and hematologic condition of the patients.Ten patients with very advanced disease in the initial period of the analysis were treated symptomatically.In five patients,venous shunts were formed to compensate for the inefficient portal system,three were qualified for intrahepatic portosystemic shunts,six for liver transplantations, one underwent recanalization of the impatent hepatic vein with radiological technique.Twelve patients with incomplete impatency of hepatic veins were treated conservatively.In 7 cases,fibrinolytic treatment for secondary portal thrombosis was instituted.The patients ’age and sex,etiology of the syndrome,clinical course,results of imaging studies and treatment were analyzed.The follow-up time ranged from 2 months to 8 years (mean:34 months). Women with hematologic disorders predominated among the patients.In all the cases,the characteristic symptoms included pain, ascites and hepatosplenomegaly, with additional portal hypertension and hepatic failure at the later stages of the disease. Ultrasonography is an essential diagnostic method used in Budd-Chiari syndrome.Fifteen of the observed patients died,including two cases of postoperative mortality. Budd-Chiari syndrome is a rare pathology of various etiology.The first symptoms include pain,ascites and hepatosplenomegaly. Ultrasonography is an essential diagnostic method.Formation of venous shunts and liver transplantation are effective methods of treatment in selected cases.Polycythemia increases the risk of postoperative complications.Early-onset secondary portal thrombosis provides indication for fibrinolytic treatment

Keywords: Budd-Chiari syndrome, portal thrombosis, thrombolytic treatment

Add Comment 0 Comments

Editorial

01 February 2024 : Editorial  

Editorial: Global Health Concerns as Vaccine-Preventable Infections Including SARS-CoV-2 (JN.1), Influenza, Respiratory Syncytial Virus (RSV), and Measles Continue to Rise

Dinah V. Parums

DOI: 10.12659/MSM.943911

Med Sci Monit 2024; 30:e943911

0:00

In Press

02 Jan 2024 : Clinical Research  

Urinary Concentration of Renal Biomarkers in Healthy Term Neonates: Gender Differences in GST-pi Excretion

Med Sci Monit In Press; DOI: 10.12659/MSM.942819  

0:00

29 Dec 2023 : Clinical Research  

Performance of Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) in Chinese Population with Prima...

Med Sci Monit In Press; DOI: 10.12659/MSM.942747  

08 Jan 2024 : Review article  

Review of Approaches to the Management of Vertical Dental Root Fractures and Tooth Preservation

Med Sci Monit In Press; DOI: 10.12659/MSM.943100  

03 Jan 2024 : Clinical Research  

Comparative Efficacy of Ultrasound-Guided Cervical Fascial Infiltration versus Periarticular Administration...

Med Sci Monit In Press; DOI: 10.12659/MSM.942044  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750