01 July 2005 : Extended abstract from EFAS 2011
Possible induction of oral allergy syndrome during specific immunotherapy inpatients sensitive to tree pollen.
Marek Modrzyński, Edward ZawiszaMed Sci Monit 2005; 11(7): CR351-355 :: ID: 16984
Abstract
Background: Many studies have shown that specific immunotherapy may preventthe development of allergies to new allergens. Recently, however, there have been sporadic reports onthe possibility of new allergies developing during immunotherapy. The aim of this study was to evaluatethe possibility of the occurrence of food allergy and changes of sIgE concentration in patients sensitiveto tree pollen during specific immunotherapy Material/Methods: We examined 12 patients subjected to desensitizationtreatment of pollinosis caused by allergy to the pollen of Betulaceae trees, in whom only Bet v 1 sIgEwas found in serum prior to immunotherapy. The control group included 8 allergic patients who did notconsent to this treatment. Results: Bet v 2 sIgE was detected after 6 months in 3 patients (25%) andafter 18 months in another 2 patients (41.7% total). In 2 cases, oral allergy syndrome (OAS) occurredin the course of therapy. These findings were accompanied by a concomitant decrease in nasal and ocularallergic signs during the birch pollen season in the overwhelming majority of patients (91.7%). In thecontrol group, no serum occurrence of Bet v 2 sIgE was found during the 18-month observation period.Although no OAS signs appeared in any patient, the symptomatic intensity of pollinosis was not reduced.Conclusions: Due to the limitations of currently used vaccines, new allergies may be induced during immunotherapy.In sporadic cases these may be accompanied by the occurrence of specific clinical manifestations, usuallymild.
Keywords: Betula - immunology, Desensitization, Immunologic - adverse effects, Food Hypersensitivity - etiology, Food Hypersensitivity - immunology, Hypersensitivity - immunology, Hypersensitivity - therapy, Immunoglobulin E - blood, Pollen - immunology, Syndrome, Betula - immunology, Desensitization, Immunologic - adverse effects, Food Hypersensitivity - immunology, Hypersensitivity - therapy, Immunoglobulin E - blood, Pollen - immunology, Syndrome
Editorial
01 April 2025 : Editorial
Editorial: Rapid Testing for the Avian Influenza A(H5N1) Virus is Urgently Required as Infections in Poultry and Dairy Cows are on the Rise, and so is Transmission to HumansDOI: 10.12659/MSM.949109
Med Sci Monit 2025; 31:e949109
In Press
Clinical Research
Longitudinal Evaluation of Metabolic Benefits of Inactivated COVID-19 Vaccination in Diabetic Patients in T...Med Sci Monit In Press; DOI: 10.12659/MSM.947450
Clinical Research
Impact of Voltage Level on Hospitalization and Mortality in Electrical Injury Cases: A Retrospective Analys...Med Sci Monit In Press; DOI: 10.12659/MSM.947675
Clinical Research
Comparative Study of Plantar Load and Foot Posture Characteristics in Male Elite Squash Players and Non-Ath...Med Sci Monit In Press; DOI: 10.12659/MSM.947828
Clinical Research
Dental Students’ Opinions on Use of Artificial Intelligence: A Survey StudyMed Sci Monit In Press; DOI: 10.12659/MSM.947658
Most Viewed Current Articles
17 Jan 2024 : Review article 8,071,874
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
16 May 2023 : Clinical Research 702,992
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Mar 2024 : Editorial 30,169
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and ...DOI :10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
28 Jan 2024 : Review article 24,060
A Review of IgA Vasculitis (Henoch-Schönlein Purpura) Past, Present, and FutureDOI :10.12659/MSM.943912
Med Sci Monit 2024; 30:e943912