Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 August 2005

Identification of schizophrenic patients by examination of body odor using gas chromatography - mass spectrometry and a cross-selective gas sensor array.

Corrado Di Natale, Roberto Paolesse, Paolo Comandini, Giorgio Pennazza, Eugenio Martinelli, Santo Rullo, Maria Roscioni, Claudio Roscioni, Alessandro Finazzi-Agro

Med Sci Monit 2005; 11(8): CR366-375 :: ID: 201285


Background: Previous findings have shown that the body odor of patientsaffected by schizophrenia contains some specific compounds. Chemical sensor technology has proved tobe able to classify different odours. We investigated the possibility of using a chemical sensor arrayto detect body odor alteration in schizophrenic patients. Material/Methods: The sweat of subjects wassampled and analysed by Gas Chromatography-Mass Spectrometry (GC-MS) and by an array of cross-selectivegas sensors. A total of 27 individuals were involved in the experiment: 9 schizophrenics, 9 with othermental disorders, and 9 controls. Results: GC-MS analysis showed a richer composition for the sweat ofschizophrenic patients. Nevertheless, the individuation of specific markers was unsuccessful. On theother hand, statistical analysis of cross-selective gas sensor data provided a complete classificationof schizophrenic patients with respect to the other three groups. Conclusions: The alteration of bodyodor in schizophrenic patients was confirmed by GC-MS and chemical sensor array. Results show that thealteration is complex and cannot be limited to a single compound, but rather to a global variation ofthe body odor.

Keywords: Schizophrenia - classification, Gas Chromatography-Mass Spectrometry - methods, Gases - analysis, Odors - analysis, Schizophrenia - metabolism, Sensitivity and Specificity

Add Comment 0 Comments

788 19


01 December 2023 : Editorial  

Editorial: Outbreaks of Post-Pandemic Childhood Pneumonia and the Re-Emergence of Endemic Respiratory Infections

Dinah V. Parums

DOI: 10.12659/MSM.943312

Med Sci Monit 2023; 29:e943312


In Press

08 Dec 2023 : Clinical Research  

Association Between Influenza Vaccine Uptake and Health Awareness: A Cross-Sectional Questionnaire-Based St...

Med Sci Monit In Press; DOI:  

04 Dec 2023 : Animal Research  

Effects of Intrathecal Ketamine on Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor and Mech...

Med Sci Monit In Press; DOI:  

01 Dec 2023 : Clinical Research  

Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St...

Med Sci Monit In Press; DOI:  

30 Nov 2023 : Review article  

Decoding the Neurological Sequelae of General Anesthesia: A Review

Med Sci Monit In Press; DOI:  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750