Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

11 March 2002

Cat-scratch disease in an immunocompromised host.

Igor Alexander Harsch, Simin Pour Schahin, Alexander Schmelzer, Eckhart Georg Hahn, Peter Christopher Konturek

Med Sci Monit 2002; 8(3): CS26-29 :: ID: 420899


BACKGROUND: The main causative agents of cat-scratch disease are Bartonellahenselae, tiny, gram-negative bacilli. The disease usually has a benign course with the development ofa papule at the inoculation site, followed by regional lymphadenopathy. In most cases, complete resolutionoccurs, but in immunocompromised hosts, the course of the disease can be aggravated. CASE REPORT: A patientreceived methotrexate and corticosteroids for 3 months due to rheumatoid arthritis. He developed fever,exanthema and leukopenia under methotrexate therapy. Dark red indurations with central ulcerations athis right thigh revealed a further problem apart from the methotrexate-induced leucopenia and immunosuppression.The ulcerations were the remainders of recurrent scratches from the patient's cat. The patient's antibodytiters against Bartonella henselae remained low and inguinal lymph node swelling was only for a shorttime to be observed, this reaction obviously weakened as a result of the immunosuppression. However,the typical course, the exclusion of other reasons for the exanthema and the rapid improvement of thepatient's condition after antibiotic treatment ascertained the diagnosis. CONCLUSIONS: In immunocompromisedhosts, diseases with a typically benign course can become severe and life-threatening illnesses. Ownershipof pets should be taken into consideration before onset of an immunosuppressive therapy.

Keywords: Bartonella henselae, Cat-Scratch Disease, Cats, Immunocompromised Host, Immunosuppression, Immunosuppressive Agents

Add Comment 0 Comments


01 July 2024 : Editorial  

Editorial: The Global Threats of Increasing Antimicrobial Resistance Require New Approaches to Drug Development, Including Molecular Antimicrobial Adjuvants

Dinah V. Parums

DOI: 10.12659/MSM.945583

Med Sci Monit 2024; 30:e945583


In Press

Clinical Research  

Cost-Effectiveness Analysis of Hepatic Arterial Chemotherapy for Advanced Hepatocellular Carcinoma in China...

Med Sci Monit In Press; DOI: 10.12659/MSM.944526  


Clinical Research  

Comparative Analysis of Antihypertensive and Anticonvulsant Regimens in Managing Pre-eclampsia and Eclampsi...

Med Sci Monit In Press; DOI: 10.12659/MSM.944985  

Clinical Research  

Reduced Radial Artery Occlusion in Transradial Cerebral Angiography: Key Predictive Factors and Preventive ...

Med Sci Monit In Press; DOI: 10.12659/MSM.944297  

Database Analysis  

Enhanced Outcomes in Femoral Subtrochanteric Fractures Using Long INTERTAN Nails with Titanium Cable Cercla...

Med Sci Monit In Press; DOI: 10.12659/MSM.944383  

Most Viewed Current Articles

17 Jan 2024 : Review article   4,116,598

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799


14 Dec 2022 : Clinical Research   1,594,331

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


16 May 2023 : Clinical Research   691,000

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387


01 Jan 2022 : Editorial   50,822

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750