Abstract

BACKGROUND: The aim of our research was to evaluate TPS concentration asa marker of proliferative processes and the levels of CEA in children and adults with ulcerative colitis(UC) and in adults with colorectal adenocarcinoma (AC), to find out if there is any interdependence betweenTPS and CEA concentrations in these patients and to evaluate the usefulness of TPS as a marker of neoplasticrisk in patients with UC. MATERIAL/METHODS: The study was carried out in 3 groups of patients: GroupI consisted of 15 children, ages 10-18, treated for UC; Group II, 22 adults, ages 23-40, treated forUC; and Group III, 14 patients, ages 40-60, in whom AC was diagnosed. RESULTS: In Group II, the meanTPS concentration was significantly higher than in Group I (p

Keywords: Adenocarcinoma, Adolescent, Carcinoembryonic Antigen, Child, Colitis, Ulcerative, Peptides, Tumor Markers, Biological