Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

31 December 1969

Nitric oxide synthase type 1 expression in human lung cancer and its relation to p53.

Barbara Lewko, Albina Zółtowska, Jan Stepiński, Maciej Kamiński, Jan Skokowski, Andrzej Roszkiewicz, Grażyna Moszkowska

Med Sci Monit 2001; 7(2): BR218-221 :: ID: 421160

Abstract

BACKGROUND: The nitric oxide synthases (NOS) have been observed in humantumour cell lines as well as in solid tumours. Neuronal isoform of NOS (NOS1) was particularly abundantin low-differentiated gynaecological, breast and central nerve system tumours, suggesting that it maycharacterize poorly differentiated tumours. So far, little is known about expression of the neuronalNOS isoform in non-small cell lung cancer. Our aim was to compare NOS1 expression in non-small lung carcinomaswith respect to tumor staging and p53 protein expression.
MATERIAL AND METHODS: Thirty-two cases of non-smalllung carcinomas of all grades of malignancy and ten control lung specimens with neoplastic lesions wereexamined. Paraffin-embedded tissues were stained with hematoxylin and eosin, or with antibodies to NOS1and p53, and evaluated under light microscope.
RESULTS: No statistical correlation between expressionof p53, NOS1 and degree od tumour differentiation was observed.
CONCLUSION: Expression of NOS1 can notserve as a marker for highly malignant tumours in the non-small cell lung carcinomas.

Keywords: NOS1, granular pattern, perinuclear bead-like pattern, lung cancers

Comments
Error 404
Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

Page Not Found

The page you are looking for was not found. Please use the search engine or the website menu.

Latest Articles

#936446

26 May 2022 : Clinical Research  

Evaluation of Patients with Angiographically-Confirmed Coronary Artery Disease to Investigate the Association Between Epicardial Fat Thickness and Atrial Fibrillation

Xiaoxia Xu, Qina Zhou [...]

DOI: 10.12659/MSM.936446

Med Sci Monit 2022; 28:e936446

#936446

26 May 2022 : Clinical Research  

Evaluation of Patients with Angiographically-Confirmed Coronary Artery Disease to Investigate the Association Between Epicardial Fat Thickness and Atrial Fibrillation

Xiaoxia Xu, Qina Zhou [...]

Department of Cardiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China (mainland)

DOI: 10.12659/MSM.936446

Med Sci Monit 2022; 28:e936446

#935823

25 May 2022 : Meta-Analysis  

Effect of the COVID-19 Pandemic on Serum Vitamin D Levels in People Under Age 18 Years: A Systematic Review and Meta-Analysis

Xian Cui, Yuhang Zhai [...]

DOI: 10.12659/MSM.935823

Med Sci Monit 2022; 28:e935823

#935823

25 May 2022 : Meta-Analysis  

Effect of the COVID-19 Pandemic on Serum Vitamin D Levels in People Under Age 18 Years: A Systematic Review and Meta-Analysis

Xian Cui, Yuhang Zhai [...]

DOI: 10.12659/MSM.935823

Med Sci Monit 2022; 28:e935823

#935515

24 May 2022 : Database Analysis  

Identification of Key Genes and Key Pathways in Breast Cancer Based on Machine Learning

Shurui Bao, Guijin He

DOI: 10.12659/MSM.935515

Med Sci Monit 2022; 28:e935515

#935515

24 May 2022 : Database Analysis  

Identification of Key Genes and Key Pathways in Breast Cancer Based on Machine Learning

Shurui Bao, Guijin He

DOI: 10.12659/MSM.935515

Med Sci Monit 2022; 28:e935515

#935455

23 May 2022 : Clinical Research  

Microalbuminuria Complicated with Low Estimated Glomerular Filtration Rate: Early Risk Factors for Contrast-Induced Acute Kidney Injury After Coronary Intervention

Meijuan Hu, Erfei Luo [...]

DOI: 10.12659/MSM.935455

Med Sci Monit 2022; 28:e935455

#935455

23 May 2022 : Clinical Research  

Microalbuminuria Complicated with Low Estimated Glomerular Filtration Rate: Early Risk Factors for Contrast-Induced Acute Kidney Injury After Coronary Intervention

Meijuan Hu, Erfei Luo [...]

DOI: 10.12659/MSM.935455

Med Sci Monit 2022; 28:e935455

#936246

21 May 2022 : Clinical Research  

Curative Analysis of Patients with Hepatocellular Carcinoma Using Transcatheter Arterial Chemoembolization Combined with Radiofrequency Ablation

Yifan Li, Diwen Zhu [...]

DOI: 10.12659/MSM.936246

Med Sci Monit 2022; 28:e936246

#936246

21 May 2022 : Clinical Research  

Curative Analysis of Patients with Hepatocellular Carcinoma Using Transcatheter Arterial Chemoembolization Combined with Radiofrequency Ablation

Yifan Li, Diwen Zhu [...]

DOI: 10.12659/MSM.936246

Med Sci Monit 2022; 28:e936246

#936495

20 May 2022 : Clinical Research  

Importance of Influenza Anti-Hemagglutinin Antibodies During the SARS-CoV-2 Pandemic in the 2019/2020 Epidemic Season in Poland

Lidia B. Brydak, Karol Szymański [...]

DOI: 10.12659/MSM.936495

Med Sci Monit 2022; 28:e936495

#936495

20 May 2022 : Clinical Research  

Importance of Influenza Anti-Hemagglutinin Antibodies During the SARS-CoV-2 Pandemic in the 2019/2020 Epidemic Season in Poland

Lidia B. Brydak, Karol Szymański [...]

DOI: 10.12659/MSM.936495

Med Sci Monit 2022; 28:e936495

#935426

19 May 2022 : Animal Research  

Anti-Inflammatory and Anti-Oxidative Effects of Isorhamnetin for Protection Against Lung Injury in a Rat Model of Heatstroke in a Dry-Heat Environment

Xiang Dong, Jia-Jia Li [...]

DOI: 10.12659/MSM.935426

Med Sci Monit 2022; 28:e935426

#935426

19 May 2022 : Animal Research  

Anti-Inflammatory and Anti-Oxidative Effects of Isorhamnetin for Protection Against Lung Injury in a Rat Model of Heatstroke in a Dry-Heat Environment

Xiang Dong, Jia-Jia Li [...]

DOI: 10.12659/MSM.935426

Med Sci Monit 2022; 28:e935426

#936327

18 May 2022 : Database Analysis  

Technique Innovation and Clinical Application of Electrical Impedance Tomography: Bibliometric Research from 2001 to 2020

Li Xiao, Kang Yu [...]

DOI: 10.12659/MSM.936327

Med Sci Monit 2022; 28:e936327

#936327

18 May 2022 : Database Analysis  

Technique Innovation and Clinical Application of Electrical Impedance Tomography: Bibliometric Research from 2001 to 2020

Li Xiao, Kang Yu [...]

DOI: 10.12659/MSM.936327

Med Sci Monit 2022; 28:e936327

#935807

17 May 2022 : Database Analysis  

Relationship Between C-Reactive Protein and Respiratory Diseases in Patients with Type 2 Diabetic Retinopathy

Kejia Chen, Jiamin Yan [...]

DOI: 10.12659/MSM.935807

Med Sci Monit 2022; 28:e935807

#935807

17 May 2022 : Database Analysis  

Relationship Between C-Reactive Protein and Respiratory Diseases in Patients with Type 2 Diabetic Retinopathy

Kejia Chen, Jiamin Yan [...]

DOI: 10.12659/MSM.935807

Med Sci Monit 2022; 28:e935807

#935664

16 May 2022 : Review article  

A Review of the Role of the Antiplatelet Drug Ticagrelor in the Management of Acute Coronary Syndrome, Acute Thrombotic Disease, and Other Diseases

Luyuan Tao, Shijia Ren [...]

DOI: 10.12659/MSM.935664

Med Sci Monit 2022; 28:e935664

#935664

16 May 2022 : Review article  

A Review of the Role of the Antiplatelet Drug Ticagrelor in the Management of Acute Coronary Syndrome, Acute Thrombotic Disease, and Other Diseases

Luyuan Tao, Shijia Ren [...]

DOI: 10.12659/MSM.935664

Med Sci Monit 2022; 28:e935664

#936037

15 May 2022 : Database Analysis  

Bibliometric Visualization Analysis of Microbiome-Gut-Brain Axis from 2004 to 2020

Hui Wang, Tianlin Long [...]

DOI: 10.12659/MSM.936037

Med Sci Monit 2022; 28:e936037

#936037

15 May 2022 : Database Analysis  

Bibliometric Visualization Analysis of Microbiome-Gut-Brain Axis from 2004 to 2020

Hui Wang, Tianlin Long [...]

DOI: 10.12659/MSM.936037

Med Sci Monit 2022; 28:e936037

#936425

14 May 2022 : Clinical Research  

Case-Control Study to Investigate the Association Between Serum Apolipoprotein B/A1 Ratio and Atrial Fibrillation by Sex in 920 Patients from China

Xia Zhong, Huachen Jiao [...]

DOI: 10.12659/MSM.936425

Med Sci Monit 2022; 28:e936425

#936425

14 May 2022 : Clinical Research  

Case-Control Study to Investigate the Association Between Serum Apolipoprotein B/A1 Ratio and Atrial Fibrillation by Sex in 920 Patients from China

Xia Zhong, Huachen Jiao [...]

DOI: 10.12659/MSM.936425

Med Sci Monit 2022; 28:e936425

Editorial

01 May 2022 : Editorial  

Editorial: Cardiovascular Complications at One Year After SARS-CoV-2 Infection are Independent of Underlying Cardiovascular Risk Factors or Severity of COVID-19

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.937048

Med Sci Monit 2022; 28:e937048

SARS-CoV-2/COVID-19

24 May 2022 : Clinical Research  

Screening for SARS-CoV-2 Infection in Students at the Medical University of Warsaw, Poland Between November...

Med Sci Monit In Press; DOI: 10.12659/MSM.936962  

04 May 2022 : Clinical Research  

Effects of Wearing Face Masks on Exercise Capacity and Ventilatory Anaerobic Threshold in Healthy Subjects ...

Med Sci Monit In Press; DOI: 10.12659/MSM.936069  

22 April 2022 : Clinical Research  

Factors Associated with Falls During Hospitalization for Coronavirus Disease 2019 (COVID-19)

Med Sci Monit In Press; DOI: 10.12659/MSM.936547  

In Press

25 May 2022 : Review article  

Narrative Review of the Mechanism of Hip Prosthesis Dislocation and Methods to Reduce the Risk of Dislocation

Med Sci Monit In Press; DOI: 10.12659/MSM.935665  

24 May 2022 : Clinical Research  

Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing ...

Med Sci Monit In Press; DOI: 10.12659/MSM.936580  

24 May 2022 : Clinical Research  

Screening for SARS-CoV-2 Infection in Students at the Medical University of Warsaw, Poland Between November...

Med Sci Monit In Press; DOI: 10.12659/MSM.936962  

23 May 2022 : Clinical Research  

Fully Automatic Knee Joint Segmentation and Quantitative Analysis for Osteoarthritis from Magnetic Resonanc...

Med Sci Monit In Press; DOI: 10.12659/MSM.936733  

Most Viewed Current Articles

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750

Editorial

04 June 2022 : Editorial  

Editorial: Acute Hepatitis of Unknown Origin in Children. Is Autoimmunity at Play?

Nahum Mendez-Sanchez, Shreya C. Pal
Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

DOI: 10.12659/MSM.937371

Med Sci Monit 2022; 28:e937371

In Press

23 Jun 2022 : Clinical Research  

A Real-World Study to Compare the Safety and Efficacy of Paritaprevir/Ombitasvir/Ritonavir and Dasabuvir, w...

Med Sci Monit In Press; DOI: 10.12659/MSM.936706  

22 Jun 2022 : Clinical Research  

A Single-Center Study Comparing the Effects of Thoracic Spine Manipulation vs Mobility Exercises in 26 Offi...

Med Sci Monit In Press; DOI: 10.12659/MSM.937316  

21 Jun 2022 : Clinical Research  

Optimal Timing and Outcomes of Minimally Invasive Approach in Acute Biliary Pancreatitis

Med Sci Monit In Press; DOI: 10.12659/MSM.937016  

16 Jun 2022 : Clinical Research  

Renal Manifestations in Inflammatory Bowel Disease: A Cohort Study During the Biologic Era

Med Sci Monit In Press; DOI: 10.12659/MSM.936497  

Most Viewed Current Articles

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750