01 September 2003
Med Sci Monit 2003; 9(4): 107-109 :: ID: 428665
Background: Alkaline phosphatase is an enzyme hydrolyzing monophosphate esters. The main pathologies associated with its increased activity include diseases of the liver and the skeletal system.Dramatic increases of alkaline phosphatase activity occur in infants and young children in transient hyperphosphatasemia. Material/Methods: The clinical course of 4 cases of hyperphosphatasemia in infants and young children was analyzed. The diagnoses were based on the criteria described by Kraut et al. Results: In the reported cases, increases of alkaline phosphatase activity, usually of both isoenzymes, were diagnosed accidentally during investigations performed for other reasons. The onset of the disease was preceded by infections. Other laboratory results were within normal limits specific for the patients’ age. Spontaneous normalization of alkaline phosphatase activity levels was observed during the next 2 –3 months.Conclusions: Transient hyperphosphatasemia of infants and young children is a benign condition, subsiding spontaneously without treatment. The management should be limited to periodic check-ups of alkaline phosphatase activity.
Keywords: Alkaline Phosphatase, hyperphosphatasemia, infants and children
01 February 2023 : EditorialEditorial: The XBB.1.5 (‘Kraken’) Subvariant of Omicron SARS-CoV-2 and its Rapid Global Spread
Med Sci Monit 2023; 29:e939580
19 January 2023 : Clinical ResearchEvaluation of Health-Related Quality of Life and Mental Health in 729 Medical Students in Indonesia During ...
Med Sci Monit In Press; DOI: 10.12659/MSM.938892
19 January 2023 : Clinical ResearchDetermining the Impact of the COVID-19 Pandemic on Dental Care in the Serbian Adult Population: An Online Q...
Med Sci Monit 2023; 29:e939238
27 December 2022 : Clinical ResearchEffect of Physiotherapy to Correct Rounded Shoulder Posture in 30 Patients During the COVID-19 Pandemic in ...
Med Sci Monit 2022; 28:e938926
03 Feb 2023 : Clinical ResearchTreatment of Gingival Recession Defects with Pouch and Tunnel Technique Using Connective Tissue Graft and L...
Med Sci Monit In Press; DOI: 10.12659/MSM.938865
02 Feb 2023 : Clinical ResearchOnline Questionnaire-Based Study to Evaluate the Attitudes and Use of Rubber Dental Dams by Saudi Dental Pr...
Med Sci Monit In Press; DOI: 10.12659/MSM.938672
02 Feb 2023 : Database AnalysisPrognostic-Related Biomarkers in Pancreatic Ductal Adenocarcinoma Correlating with Immune Infiltrates Based...
Med Sci Monit In Press; DOI: 10.12659/MSM.938785
Most Viewed Current Articles
13 Nov 2021 : Clinical ResearchAcceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical ResearchRetrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review articleA Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...
Med Sci Monit 2022; 28:e936292