Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 November 2005

The effects of topical estriol and vehicle cream on the mechanical and histological properties of normal rat skin

Irfan Ozyazgan, Narin Liman, Teoman Eskitaşçioğlu

Med Sci Monit 2005; 11(11): BR405-411 :: ID: 430290

Abstract

Background: The biomechanical and histological effects of topical estriol in normal rat skin are not clearly de-fi ned, although several favourable effects of estrogens have been suggested, especially in the postmenopausal period. Our goal was to determine whether estrogens have any such effects on skin histology and biomechanical properties in an experimental rat model.
Material/Methods: Estriol cream or vehicle cream was topically applied to the dorsum of Sprague Dawley rats of both genders in three separate groups for two weeks, and the results of the estriol and vehicle groups,as well as the non-treated control groups, were compared in terms of mechanical tensometric test
results and histopathological evaluation.
Results: After the application of topical estriol, histologically, subcutis thinned (p

Keywords: Elasticity, Estriol - pharmacology, Fibrillar Collagens - drug effects, Ointments, Pharmaceutical Vehicles, Skin - drug effects

Add Comment 0 Comments

Editorial

01 November 2024 : Editorial  

Editorial: Artificial Intelligence (AI), Digital Image Analysis, and the Future of Cancer Diagnosis and Prognosis

Dinah V. Parums

DOI: 10.12659/MSM.947038

Med Sci Monit 2024; 30:e947038

0:00

In Press

Review article  

Comprehensive Insights into Arecoline Hydrobromide: Pharmacology, Toxicity, and Pharmacokinetics

Med Sci Monit In Press; DOI: 10.12659/MSM.945582  

Clinical Research  

Iliac Periosteal Bone Autografting vs Talus Non-Weight-Bearing Surgery in Hepple V Talus Osteochondral Inju...

Med Sci Monit In Press; DOI: 10.12659/MSM.944912  

Clinical Research  

Impact of Different Orthodontic Appliances on Mandibular Condyle, Anterior Region of Mandibular, and Maxill...

Med Sci Monit In Press; DOI: 10.12659/MSM.946265  

Clinical Research  

Risk Factors for Bone Cement Displacement After Percutaneous Kyphoplasty in Osteoporotic Vertebral Fracture...

Med Sci Monit In Press; DOI: 10.12659/MSM.945884  

Most Viewed Current Articles

17 Jan 2024 : Review article   6,371,831

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research   1,909,013

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

16 May 2023 : Clinical Research   695,468

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

07 Jan 2022 : Meta-Analysis   260,595

Efficacy and Safety of Light Therapy as a Home Treatment for Motor and Non-Motor Symptoms of Parkinson Dise...

DOI :10.12659/MSM.935074

Med Sci Monit 2022; 28:e935074

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750