Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 February 2006

Validity of plasma fibrinogen, D-dimer, and the von Willebrand factor as markers of cardiovascular morbidity in patients on chronic hemodialysis.

Dimitrios Kirmizis, Apostolos Tsiandoulas, Maria Pangalou, Evangelia Koutoupa, Paraskevi Rozi, Maria Protopappa, Konstantinos Barboutis

Med Sci Monit 2006; 12(2): CR55-62 :: ID: 445237

Abstract

Background: Among the non-classic cardiovascular disease risk factors inend-stage renal disease patients on chronic hemodialysis (HD), plasma fibrinogen, D-dimer, and von Willebrandfactor (vWf) levels are potential markers of cardiovascular morbidity. We designed this case-controlstudy to investigate their validity and any differences between them. Material/Methods: Twenty-five HDpatients (18 males, mean age: 63, range: 52-69 years) comprised the group with prevalent cardiovasculardisease (CVD) and 50 HD patients (35 males, mean age: 62, range: 40-77 years) with non-evident cardiovasculardisease history constituted the second study group. Twenty-five healthy non-smoking volunteers servedas controls for comparison with the study groups. Results: Patients with CVD had significantly higherconcentrations of plasma fibrinogen, D-dimer, and vWf than patients without incident CVD. All three parameterscorrelated positively with cardiovascular morbidity, i.e. fibrinogen (r=0.378, P0.001), logDD (r=0.70,P

Keywords: Cardiovascular Diseases - etiology, Biological Markers - blood, Case-Control Studies, Fibrin Fibrinogen Degradation Products - metabolism, Fibrinogen - metabolism, Kidney Failure, Chronic - therapy, Odds Ratio, Renal Dialysis, Reproducibility of Results, von Willebrand Factor - metabolism

Add Comment 0 Comments

Editorial

01 June 2024 : Editorial  

Editorial: Concerns as Highly Pathogenic Avian Influenza (HPAI) Virus of the H5N1 Subtype is Identified in Dairy Cows and Other Mammals

Dinah V. Parums

DOI: 10.12659/MSM.945315

Med Sci Monit 2024; 30:e945315

0:00

In Press

Clinical Research  

Functional Outcomes of Therapeutic Selective Nerve Root Block for Single-Segment Lumbar Spinal Stenosis: A ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943634  

Clinical Research  

Shortening Oral Simethicone-to-Colonoscopy Interval Increases Bowel Preparation Quality

Med Sci Monit In Press; DOI: 10.12659/MSM.943972  

Clinical Research  

Comparative Evaluation of Digital Cephalometric Tracing Applications on Mobile Devices and Manual Tracing

Med Sci Monit In Press; DOI: 10.12659/MSM.944628  

Clinical Research  

Impact of COVID-19-Induced Academic Stress on Insomnia and Suicidal Ideation among Taiwanese Health Trainee...

Med Sci Monit In Press; DOI: 10.12659/MSM.944932  

Most Viewed Current Articles

17 Jan 2024 : Review article   1,801,647

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research   1,532,330

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

16 May 2023 : Clinical Research   690,353

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

01 Jan 2022 : Editorial   50,289

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750