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01 February 2006

Risk factors of cardiovascular disease in GH-deficient adults with hypopituitarism: A preliminary report.

Anna Bohdanowicz-Pawlak, Jadwiga Szymczak, Joanna Bladowska, Grażyna Bednarek-Tupikowska, Bożena Bidzińska, Andrzej Milewicz

Med Sci Monit 2006; 12(2): CR75-80 :: ID: 445240

Abstract

Background: We estimated the influence of GH deficiency (GHD) in adultson chosen risk factors of cardiovascular disease and bone density. Material/Methods: Fifty-four adults(mean age: 50.4 years) with hypopituitarism were studied. We measured blood pressure, body mass index,waist-to-hip ratio, total body fat, and bone mineral density and the serum levels of lipids, glucose,insulin, pituitary hormones, estradiol, testosteron, and thyroxine, and the excretion of free cortisolin 24-h urine. GHD was confirmed with the insulin intravenous test (IIT) with a GH response to IIT of

Keywords: Cardiovascular Diseases - etiology, Case-Control Studies, Human Growth Hormone - deficiency, Hypertension - etiology, Hypopituitarism - diagnosis, Insulin - diagnostic use, Lipids - blood, Obesity - complications, Risk Factors

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750