01 May 2006
The effect of caffeic acid phenethyl ester on short-term acute myocardial ischemia.
Haluk Ince, Eyup Kandemir, Cahit Bagci, Mukaddes Gulec, Omer AkyolMed Sci Monit 2006; 12(5): BR187-193 :: ID: 450285
Abstract
Background: We previously showed that caffeic acid phenethyl ester (CAPE)attenuated NO production, reduced apoptosis, diminished serum CK and AST activities, and is cardio-protectivein rat heart subjected to ischemia/reperfusion (I/R). We now studied the short-term cardio-protectiveeffect of CAPE in an I/R rat heart model. Material/Methods: Wistar rats were divided into four groups:(i) sham-operated, (ii) I/R, (iii) I/R+CAPE, and (iv) I/R+glutathione. CAPE (10 micromol/kg) was infusedi.v. 10 min before occlusion of the left anterior descending coronary artery (8 min) followed by reperfusion(8 min). Results: SOD (p
Keywords: Malondialdehyde - metabolism, Xanthine Oxidase - metabolism, Superoxide Dismutase - metabolism, Rats, Wistar, Phenylethyl Alcohol - pharmacology, Nitric Oxide - metabolism, Myocardial Reperfusion Injury - prevention & control, Myocardial Ischemia - metabolism, Glutathione Peroxidase - metabolism, Catalase - metabolism, Cardiotonic Agents - pharmacology, Caffeic Acids - pharmacology, Antioxidants - metabolism, Adenosine Deaminase - metabolism
489 2
Editorial
01 June 2023 : Editorial
Editorial: Infectious Disease Surveillance Using Artificial Intelligence (AI) and its Role in Epidemic and Pandemic PreparednessDOI: 10.12659/MSM.941209
Med Sci Monit 2023; 29:e941209
In Press
08 Jun 2023 : Clinical Research
Risk Factors for New Vertebral Compression Fracture After Percutaneous Vertebral Augmentation: A Retrospect...Med Sci Monit In Press; DOI: 10.12659/MSM.940134
08 Jun 2023 : Clinical Research
A Nomogram for Identifying HR+/Her2- Breast Cancer Patients with Positive Sentinel Lymph Nodes and Omitted ...Med Sci Monit In Press; DOI: 10.12659/MSM.940124
08 Jun 2023 : Clinical Research
Burden of COVID-19 on Mental Health of Resident Doctors in PolandMed Sci Monit In Press; DOI: 10.12659/MSM.940208
08 Jun 2023 : Clinical Research
Risk Prediction for Rapidly Progressive Interstitial Lung Disease in Anti-MDA5-Positive Dermatomyositis: Th...Med Sci Monit In Press; DOI: 10.12659/MSM.940251
Most Viewed Current Articles
13 Nov 2021 : Clinical Research
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical Research
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...DOI :10.12659/MSM.935379
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review article
A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...DOI :10.12659/MSM.936292
Med Sci Monit 2022; 28:e936292
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952