Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 July 2006

Female fibromyalgia patients: Lower resting metabolic rates than matched healthy controls

John C. Lowe, Jackie Yellin, Gina Honeyman-Lowe

Med Sci Monit 2006; 12(7): CR282-289 :: ID: 452199

Abstract

Background: Many features of fibromyalgia and hypothyroidism are virtuallythe same, and thyroid hormone treatment trials have reduced or eliminated fibromyalgia symptoms. Thesefindings led the authors to test the hypothesis that fibromyalgia patients are hypometabolic comparedto matched controls. Material/Methods: Resting metabolic rate (RMR) was measured by indirect calorimetryand body composition by bioelectrical impedance for 15 fibromyalgia patients and 15 healthy matched controls.Measured resting metabolic rate (mRMR) was compared to percentages of predicted RMR (pRMR) by fat-freeweight (FFW) (Sterling-Passmore: SP) and by sex, age, height, and weight (Harris-Benedict: HB). Results:Patients had a lower mRMR (4,306.31+/-1077.66 kJ vs 5,411.59+/-695.95 kJ, p=0.0028) and lower percentagesof pRMRs (SP: -28.42+/-15.82% vs -6.83+/-12.55%, p3[/sub] (FT[sub]3[/sub]) accounted for 30% of the variance in pressure-pain threshold.Conclusions: Patients had lower mRMR and percentages of pRMRs. The lower RMRs were not due to calorierestriction or low FFW. Patients' normal FFW argues against low physical activity as the mechanism. TSH,FT[sub]4[/sub], and FT[sub]3[/sub] levels did not correlate with RMRs in either group. This does not rule out inadequatethyroid hormone regulation because studies show these laboratory values do not reliably predict RMR.

Keywords: Body Composition, Basal Metabolism, Calorimetry, Case-Control Studies, Electric Impedance, Fibromyalgia - metabolism

Add Comment 0 Comments

918 14

Editorial

01 December 2023 : Editorial  

Editorial: Outbreaks of Post-Pandemic Childhood Pneumonia and the Re-Emergence of Endemic Respiratory Infections

Dinah V. Parums

DOI: 10.12659/MSM.943312

Med Sci Monit 2023; 29:e943312

0:00

In Press

01 Dec 2023 : Clinical Research  

Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St...

Med Sci Monit In Press; DOI:  

30 Nov 2023 : Review article  

Decoding the Neurological Sequelae of General Anesthesia: A Review

Med Sci Monit In Press; DOI:  

30 Nov 2023 : Clinical Research  

Enhanced Pain Relief and Muscle Growth in Individuals with Low Back Instability: The Impact of Blood Flow R...

Med Sci Monit In Press; DOI:  

29 Nov 2023 : Clinical Research  

Comparative Analysis of Intramedullary Nail versus Plate Fixation for Fibula Fracture in Supination Externa...

Med Sci Monit In Press; DOI:  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

0:00

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750