01 March 1996
The modifying effect of pineal hormones on cytochrome P-450 dependent monooxygenases system
Andrzej Plewka, Joanna Głogowska-Szeląg, Barbara Buntner, Marcin KamińskiMed Sci Monit 1996; 2(2): BR134-137 :: ID: 499545
Abstract
Melatonin, used as a parapharmaceutic agent to prevent aging processes, attracts increasingly growing attention. Therefore, we have decided to evaluate the influence of pineal hormones on hepatic metabolism. The rats were given melatonin or serotonin for 14 days. Then the activities of P-450-dependent monooxygenase system and b5, cytochrome were evaluated in the hepatic microsomal fraction. It has been shown that serotonin and melatonin decrease both the contents of P-450 cytochrome and b5 cytochrome and the activities of their reductases.
Keywords: cytochrome P-450, Melatonin, Serotonin, hepatic metabolism
363 0
Editorial
01 June 2023 : Editorial
Editorial: Infectious Disease Surveillance Using Artificial Intelligence (AI) and its Role in Epidemic and Pandemic PreparednessDOI: 10.12659/MSM.941209
Med Sci Monit 2023; 29:e941209
In Press
07 Jun 2023 : Review article
Ultrasound-Guided Brachial Plexus Block by Costoclavicular Space Approach: A Narrative ReviewMed Sci Monit In Press; DOI: 10.12659/MSM.939920
05 Jun 2023 : Clinical Research
Comparison of Texture and Color Enhancement Imaging with White Light Imaging in 52 Patients with Short-Segm...Med Sci Monit In Press; DOI: 10.12659/MSM.940249
05 Jun 2023 : Laboratory Research
Comparison of Composite Resin (Duo-Shade) Shade Guide with Vita Ceramic Shades Before and After Chemical an...Med Sci Monit In Press; DOI: 10.12659/MSM.940949
02 Jun 2023 : Database Analysis
The COVID-19 Crisis and the Incidence of Alcohol-Related Deaths in PolandMed Sci Monit In Press; DOI: 10.12659/MSM.940904
Most Viewed Current Articles
13 Nov 2021 : Clinical Research
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical Research
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...DOI :10.12659/MSM.935379
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review article
A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...DOI :10.12659/MSM.936292
Med Sci Monit 2022; 28:e936292
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952