Abstract

Disorders of haemostasis seem to play an important role in the pathogenesis of ischaemic heart disease. The aim of our study was to evaluate and compare selected haemostatic variables in 58 patients over 50 years of age with stable angina pectoris and 21 healthy individuals of comparable age. The following were evaluated: the activated partial thromboplastin time (APTTratio), prothrombin time (PT-INR), thrombin time (TT-sec), fibrinogen concentration (Fb-mg%), antithrombin III activity (ATIII-%), plasminogen activity (PLG-%) and alpha-2-antiplasmin activity (ATPL-%), euglobulin clot lysis time (LIZ-min), platelet count (PLT-thousand/mm3,), mean platelet volume (MPV-fl) and ADPinduced platelet aggregation in vitro (AGR-%). We did not observe any significant differences in the above haemostatic variables between patients with stable angina pectoris and normal individuals.

Keywords: stable angina pectoris, haemostasis