01 May 1997
Soluble HLA class I antigens (s-HLA-I) in osteporotic patients sera
Gabriel Turowski, Anna Kędzierska, Danuta Gieracka-Pażucha, Joanna Flasza, Lidia RutowiczMed Sci Monit 1997; 3(3): CR373-377 :: ID: 501141
Abstract
In the sera of 20 patients with radiographically diagnosed 3rd degree osteoporosis (type I-post menopausal, type II-of elderly age) concentrations of soluble HLA-class I antigens were determined. In these patients, HLA-ABC phenotypes were first identified, then levels of sHLA-I were determined in a semiquantitative test of lymphocytotoxic reaction inhibition according to Tait et al. and McLean et al. with our modification. Varying sHLA-I concentrations were obtained for the majority of examined HLA specificities encoded by HLA-A, B and C loci in these patients. The results were compared with similar measurements in a control population of 205 healthy unrelated adults. A statistically significant difference was shown for HLA-B27 and HLA-B44 .
Keywords: soluble HLA antigens, sHLA, Osteoporosis
660 0
Editorial
01 November 2023 : Editorial
Editorial: Factors Driving New Variants of SARS-CoV-2, Immune Escape, and Resistance to Antiviral Treatments as the End of the COVID-19 Pandemic is DeclaredDOI: 10.12659/MSM.942960
Med Sci Monit 2023; 29:e942960
In Press
30 Nov 2023 : Review article
Decoding the Neurological Sequelae of General Anesthesia: A ReviewMed Sci Monit In Press; DOI: 10.12659/MSM.942740
30 Nov 2023 : Clinical Research
Enhanced Pain Relief and Muscle Growth in Individuals with Low Back Instability: The Impact of Blood Flow R...Med Sci Monit In Press; DOI: 10.12659/MSM.942508
29 Nov 2023 : Clinical Research
Comparative Analysis of Intramedullary Nail versus Plate Fixation for Fibula Fracture in Supination Externa...Med Sci Monit In Press; DOI: 10.12659/MSM.941909
29 Nov 2023 : Clinical Research
Impact of COVID-19 on Academic Burnout among Medical College Students in China: Findings from a Web-Based S...Med Sci Monit In Press; DOI: 10.12659/MSM.942317
Most Viewed Current Articles
13 Nov 2021 : Clinical Research
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical Research
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...DOI :10.12659/MSM.935379
Med Sci Monit 2021; 27:e935379
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
08 Mar 2022 : Review article
A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...DOI :10.12659/MSM.936292
Med Sci Monit 2022; 28:e936292