Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

02 March 1998

Cerebral arterio-venous oxygen content differences (AVDO2) during the operations of intracranial aneurysm with isoflurane anesthesia

Zbigniew Karwacki, Paweł Słoniewski, Janina Suchorzewska

Med Sci Monit 1998; 4(2): CR297-303 :: ID: 502609


13 patients subjected to the operational treatment of intracranial aneurysm with isoflurane anaesthesia manifested haemodynamic changes in systemic and cerebral circulation. The evaluation was based upon selected parameters monitored during the operation including expiratory terminal carbon dioxide concentration (ETCO2), core temperature, mean arterial blood pressure (MABP) and cerebral arterio-venous oxygen content difference (AVDO2) - paying special attention to these parameters during the following stages of operation: I - 5 minutes before skin incision, II - 5 minutes after skin incision, III - 5 minutes after meningotomy, IV - 5 minutes after clipping the aneurysm, V - 5 minutes after meningorrhaphy. In the subsequent stages of operation, MABP mean values fluctuated statistically significantly, and there was a negative linear correlation with statistically significant changes of mean AVDO2 values (r=-9107, p<0.05). On the basis of the analysis of mean PaCO2,ETCO2,PjCO2, and core temperature it may be claimed that there is no significant influence of these parameters upon cerebral blood flow and oxygen consumption by cerebral tissue. The results obtained in the present study allow for the conclusion that general complex anaesthesia with low isoflurane concentration does not ensure a full stabilisation of both systemic and cerebral circulation in the most important stages of the operation of intracranial aneurysm. It may also be claimed that the correlation of MABP with AVDO2, changes may indicate the deficiency of the autoregulation mechanism of cerebral circulation in the course of subarachnoid bleeding following the rupture of intracranial aneurysm.

Keywords: cerebral arterio-venous oxygen content, Isoflurane, neuroanaesthesia

Add Comment 0 Comments


01 June 2024 : Editorial  

Editorial: Concerns as Highly Pathogenic Avian Influenza (HPAI) Virus of the H5N1 Subtype is Identified in Dairy Cows and Other Mammals

Dinah V. Parums

DOI: 10.12659/MSM.945315

Med Sci Monit 2024; 30:e945315


In Press

Clinical Research  

Trust and Support for Cancer Research Biobanks: Insights from Cancer Patients in Poland

Med Sci Monit In Press; DOI: 10.12659/MSM.944263  

Clinical Research  

Morphological and Dimensional Analysis of the Nasopalatine Canal: Insights from Cone-Beam Computed Tomograp...

Med Sci Monit In Press; DOI: 10.12659/MSM.944424  

Clinical Research  

Hemorrhagic Cysts in the Pancreas: Risk Factors, Treatment, and Outcomes – Insights from a Single-Center Study

Med Sci Monit In Press; DOI: 10.12659/MSM.941955  

Clinical Research  

Perioperative Administration of Tranexamic Acid and Low Molecular Weight Heparin for Enhanced Blood Managem...

Med Sci Monit In Press; DOI: 10.12659/MSM.944063  

Most Viewed Current Articles

14 Dec 2022 : Clinical Research   1,421,178

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


17 Jan 2024 : Review article   1,355,487

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799


16 May 2023 : Clinical Research   690,090

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387


01 Jan 2022 : Editorial   50,113

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750