Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 January 1998

Human epidermal growth factor serum concentration levels during puberty

Beata Kulik-Rechberger, Tomasz Rechberger, Maria Kozłowska, Hanna Chrząˆstek-Spruch

Med Sci Monit 1998; 4(1): CR117-121 :: ID: 502840

Abstract

Serum concentrations of human epidermal growth factor (hEGF) were investigated upon during the increased pubertal growth spurt. One hundred and six girls aged between 9.8 to 15.5 were divided, after physical examination, into three groups according to their developmental stage of puberty (breast Tanner stage). hEGF was determined by the RIA method using kits from Amersham (code IM. 1961). Twenty one girls (mean age 10.9 years, weight 30.62±3.84 kg, height 139.5±4.3 cm) were in the first group-stage 1 of breast development (bd).Forty four girls (mean age 12.0±1.2 years, weight 38.41±7.32 kg, height 151.0±8.7 cm) were in the second group, undergoing pubertal growth spurt-stage 2 and 3 of bd. Forty one girls (mean age 13.8±0.8 years, weight 52.10±6.67 kg, height 160.9±5.8 cm) were in the third group-stage 4 and 5 of bd. The mean serum concentration level of hEGF in the first group was 0.282±0.130 ng/ml, 0.271±0.126 ng/ml in the second group and 0.232±0.073 ng/ml in the third group respectively, but the differences were not statistically significant (group I vs. group III - pp<0.061, group II vs. III - p<0.082). We did not find any correlation between serum concentration levels of hEGF and the physical parameters of increased growth during puberty. Therefore, we concluded that serum concentration levels of hEGF cannot be used as a predictor for increased growth during puberty.

Keywords: human epidermal growth factor, Puberty

Add Comment 0 Comments

Editorial

01 April 2024 : Editorial  

Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug Resistance

Dinah V. Parums

DOI: 10.12659/MSM.944600

Med Sci Monit 2024; 30:e944600

0:00

In Press

05 Apr 2024 : Clinical Research  

Comparative Analysis of Transoral Endoscopic Parathyroidectomy Vestibular Approach and Focused Open Surgery...

Med Sci Monit In Press; DOI: 10.12659/MSM.944128  

0:00

05 Mar 2024 : Clinical Research  

Muscular Function Recovery from General Anesthesia in 132 Patients Undergoing Surgery with Acceleromyograph...

Med Sci Monit In Press; DOI: 10.12659/MSM.942780  

05 Mar 2024 : Clinical Research  

Effects of Thermal Insulation on Recovery and Comfort of Patients Undergoing Holmium Laser Lithotripsy

Med Sci Monit In Press; DOI: 10.12659/MSM.942836  

05 Mar 2024 : Clinical Research  

Role of Critical Shoulder Angle in Degenerative Type Rotator Cuff Tears: A Turkish Cohort Study

Med Sci Monit In Press; DOI: 10.12659/MSM.943703  

Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750