Abstract

The paper presents a minireview on anterior experimental uveitis after systemic administration of different lipopolisccharides (LPS). LPS is a component of gram- negative bacterial membranes. Although specific ocular effects of LPS were described in the rat model by several authors, in this paper for the first time we presented an original model with Hafnia alvei endotoxin. The aim of the review is to show that experimental research such as this gives us some insight into the possible pathogenic mechanism of anterior uveitis in man.

Keywords: Animal model, anterior uveitis, bioactivity of lipopolisaccharide, endotoxin