01 January 1999
Blood fructosamine levels in patients with primary and metastatic brain tumors
Barbara Chmielewska, Ewa Belniak-Legieć, Zbigniew StelmasiakMed Sci Monit 1999; 5(1): CR58-61 :: ID: 505219
Abstract
Hyperglikemia increases the blood protein glycosylated reaction. Central nervous system (CNS) organic diseases may change the systemic metabolism. The aim of this study was to evaluate blood glycosylated protein levels (fructosamine - FA) in patients with CNS tumors. Patients were divided into two groups: those with a primary brain tumor (n=12, mean age - 58 years) and those with a metastatic brain tumor (n=12, mean age - 57.9), without diabetes or cachexy. Their protein, albumin and glucose levels were within normal values. We determined FA levels by means of the frustosamine reductive method in relation to nitrotetrazoline blue, using the Boehringer Mannheim GmbH Diagnostica set. p < 0.02 was considered as statistically significant, evaluated by means of the Mann-Whitney U test. The control group comprised 11 patients (mean age - 63.7 years). We noted an increase in fructosamine levels in patients with CNS tumors. A statistically significant difference was observed in patients with metastatic tumors, in comparison with controls (287.8 µmol/l vs. 214.9 µmol/l). An elevation in FA levels was evidence of increased glycosylation, in CNS tumor patients, due to an increase of mean glucose values in the past 2-4 weeks.
Keywords: primary brain tumors, serum fructosamine level, adults
Editorial
01 February 2023 : Editorial
Editorial: The XBB.1.5 (‘Kraken’) Subvariant of Omicron SARS-CoV-2 and its Rapid Global SpreadDOI: 10.12659/MSM.939580
Med Sci Monit 2023; 29:e939580
SARS-CoV-2/COVID-19
19 January 2023 : Clinical Research
Evaluation of Health-Related Quality of Life and Mental Health in 729 Medical Students in Indonesia During ...Med Sci Monit In Press; DOI: 10.12659/MSM.938892
19 January 2023 : Clinical Research
Determining the Impact of the COVID-19 Pandemic on Dental Care in the Serbian Adult Population: An Online Q...Med Sci Monit 2023; 29:e939238
27 December 2022 : Clinical Research
Effect of Physiotherapy to Correct Rounded Shoulder Posture in 30 Patients During the COVID-19 Pandemic in ...Med Sci Monit 2022; 28:e938926
10 December 2022 : Clinical Research
Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warn...Med Sci Monit 2022; 28:e938647
In Press
06 Feb 2023 : Clinical Research
Double C-Arm Digital Subtraction Angiography Guidance During Transjugular Intrahepatic Portosystemic Shunt ...Med Sci Monit In Press; DOI: 10.12659/MSM.938912
06 Feb 2023 : Review article
Evolution of Hybrid Intelligence and Its Application in Evidence-Based Medicine: A ReviewMed Sci Monit In Press; DOI: 10.12659/MSM.939366
03 Feb 2023 : Clinical Research
Treatment of Gingival Recession Defects with Pouch and Tunnel Technique Using Connective Tissue Graft and L...Med Sci Monit In Press; DOI: 10.12659/MSM.938865
02 Feb 2023 : Clinical Research
Online Questionnaire-Based Study to Evaluate the Attitudes and Use of Rubber Dental Dams by Saudi Dental Pr...Med Sci Monit In Press; DOI: 10.12659/MSM.938672
Most Viewed Current Articles
13 Nov 2021 : Clinical Research
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical Research
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...DOI :10.12659/MSM.935379
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review article
A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...DOI :10.12659/MSM.936292
Med Sci Monit 2022; 28:e936292
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952