Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 January 1999

Blood fructosamine levels in patients with primary and metastatic brain tumors

Barbara Chmielewska, Ewa Belniak-Legieć, Zbigniew Stelmasiak

Med Sci Monit 1999; 5(1): CR58-61 :: ID: 505219

Abstract

Hyperglikemia increases the blood protein glycosylated reaction. Central nervous system (CNS) organic diseases may change the systemic metabolism. The aim of this study was to evaluate blood glycosylated protein levels (fructosamine - FA) in patients with CNS tumors. Patients were divided into two groups: those with a primary brain tumor (n=12, mean age - 58 years) and those with a metastatic brain tumor (n=12, mean age - 57.9), without diabetes or cachexy. Their protein, albumin and glucose levels were within normal values. We determined FA levels by means of the frustosamine reductive method in relation to nitrotetrazoline blue, using the Boehringer Mannheim GmbH Diagnostica set. p < 0.02 was considered as statistically significant, evaluated by means of the Mann-Whitney U test. The control group comprised 11 patients (mean age - 63.7 years). We noted an increase in fructosamine levels in patients with CNS tumors. A statistically significant difference was observed in patients with metastatic tumors, in comparison with controls (287.8 µmol/l vs. 214.9 µmol/l). An elevation in FA levels was evidence of increased glycosylation, in CNS tumor patients, due to an increase of mean glucose values in the past 2-4 weeks.

Keywords: primary brain tumors, serum fructosamine level, adults

Add Comment 0 Comments

518 0

Editorial

01 November 2023 : Editorial  

Editorial: Factors Driving New Variants of SARS-CoV-2, Immune Escape, and Resistance to Antiviral Treatments as the End of the COVID-19 Pandemic is Declared

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville,

DOI: 10.12659/MSM.942960

Med Sci Monit 2023; 29:e942960

0:00

In Press

28 Nov 2023 : Clinical Research  

Impact of Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography on Therapeutic Decisions and ...

Med Sci Monit In Press; DOI: 10.12659/MSM.942122  

28 Nov 2023 : Clinical Research  

Long-Term Outcomes of Decompression and Grafting in Acute Pathological Proximal Femur Fractures in Children...

Med Sci Monit In Press; DOI: 10.12659/MSM.943031  

27 Nov 2023 : Clinical Research  

Comparison of Outcomes from Emergency Admissions to a Major Trauma Center in Turkey of 1646 Elderly Patient...

Med Sci Monit In Press; DOI: 10.12659/MSM.942916  

27 Nov 2023 : Clinical Research  

Evaluating Modified Ultrasound-Guided Serratus Anterior Plane Block for Enhanced Postoperative Recovery in ...

Med Sci Monit In Press; DOI: 10.12659/MSM.942757  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

0:00

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750