Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 January 1999

A typical course of Whipple's disease complicated by life-threatening condition - a case report

Maciej Świˆątkowski, Jacek Budzyński, Zofia Grˆąbczewska, Edmund Nartowicz, Jadwiga Korenkiewicz, Mirosława Adamska, Jan Domaniewski

Med Sci Monit 1999; 5(1): CS130-136 :: ID: 505275


Presented here is a case of a 29 year old patient with Whipple's disease. The first symptoms had appeared seven years before diagnosis. At the beginning, the patient complained of arthralgia. Following a symptomless period he underwent a myocardial infarction complicated by cardiogenic shock, pulmonary edema and ventricular fibrillation. Due to therapy, the patients state improved, but during the follow-up period related to antibiotic treatment, we observed an increase in the akinetic and hypokinetic area of the myocardium as well as in the pressure of the pulmonary artery. Following one year, diarrhea, loss of body mass and malabsorption symptoms appeared. We observed an increase in the hypokinetic area of the myocardium and pulmonary pressure. During the diagnostic process, we performed endoscopy of the upper part of the digestive tract. Based on the endoscopy, as well as on light and electron microscope examinations of the duodenal mucosa, we diagnosed Whipple's disease. Following penicillin treatment, the patients state improved and we observed withdrawal or reduction of previously seen ecg and echocardiographic changes. Based on the above mentioned, we concluded that the cardiologic symptoms of our patient, were a result of a myocardial inflammatory process during the course of Whipple's disease.

Keywords: hemorrhagia, Whipple

Add Comment 0 Comments


01 June 2024 : Editorial  

Editorial: Concerns as Highly Pathogenic Avian Influenza (HPAI) Virus of the H5N1 Subtype is Identified in Dairy Cows and Other Mammals

Dinah V. Parums

DOI: 10.12659/MSM.945315

Med Sci Monit 2024; 30:e945315


In Press

Clinical Research  

Anterior Plate-Supported Cannulated Screw Surgery for Ankle Arthrodesis: Clinical and Radiologic Results in...

Med Sci Monit In Press; DOI: 10.12659/MSM.944452  

Clinical Research  

Elevated Plasma Levels of Growth Arrest Specific 6 (Gas6) Protein in Severe Obesity: Implications for Adipo...

Med Sci Monit In Press; DOI: 10.12659/MSM.944462  

Database Analysis  

Systemic Immune-Inflammation Index (SII) as a Predictor of Short-Term Mortality Risk in Sepsis-Associated A...

Med Sci Monit In Press; DOI: 10.12659/MSM.943414  

Clinical Research  

Morphological Variations of the Nasopalatine Canal in the North Cyprus Population: A Cone Beam Computed Tom...

Med Sci Monit In Press; DOI: 10.12659/MSM.944868  

Most Viewed Current Articles

17 Jan 2024 : Review article   2,131,100

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799


14 Dec 2022 : Clinical Research   1,555,090

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


16 May 2023 : Clinical Research   690,471

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387


01 Jan 2022 : Editorial   50,389

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750