Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 January 1999

A typical course of Whipple's disease complicated by life-threatening condition - a case report

Maciej Świˆątkowski, Jacek Budzyński, Zofia Grˆąbczewska, Edmund Nartowicz, Jadwiga Korenkiewicz, Mirosława Adamska, Jan Domaniewski

Med Sci Monit 1999; 5(1): CS130-136 :: ID: 505275


Presented here is a case of a 29 year old patient with Whipple's disease. The first symptoms had appeared seven years before diagnosis. At the beginning, the patient complained of arthralgia. Following a symptomless period he underwent a myocardial infarction complicated by cardiogenic shock, pulmonary edema and ventricular fibrillation. Due to therapy, the patients state improved, but during the follow-up period related to antibiotic treatment, we observed an increase in the akinetic and hypokinetic area of the myocardium as well as in the pressure of the pulmonary artery. Following one year, diarrhea, loss of body mass and malabsorption symptoms appeared. We observed an increase in the hypokinetic area of the myocardium and pulmonary pressure. During the diagnostic process, we performed endoscopy of the upper part of the digestive tract. Based on the endoscopy, as well as on light and electron microscope examinations of the duodenal mucosa, we diagnosed Whipple's disease. Following penicillin treatment, the patients state improved and we observed withdrawal or reduction of previously seen ecg and echocardiographic changes. Based on the above mentioned, we concluded that the cardiologic symptoms of our patient, were a result of a myocardial inflammatory process during the course of Whipple's disease.

Keywords: hemorrhagia, Myocardial Infarction, Whipple

Add Comment 0 Comments

587 1


01 November 2023 : Editorial  

Editorial: Factors Driving New Variants of SARS-CoV-2, Immune Escape, and Resistance to Antiviral Treatments as the End of the COVID-19 Pandemic is Declared

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville,

DOI: 10.12659/MSM.942960

Med Sci Monit 2023; 29:e942960


In Press

28 Nov 2023 : Clinical Research  

Impact of Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography on Therapeutic Decisions and ...

Med Sci Monit In Press; DOI: 10.12659/MSM.942122  

28 Nov 2023 : Clinical Research  

Long-Term Outcomes of Decompression and Grafting in Acute Pathological Proximal Femur Fractures in Children...

Med Sci Monit In Press; DOI: 10.12659/MSM.943031  

27 Nov 2023 : Clinical Research  

Comparison of Outcomes from Emergency Admissions to a Major Trauma Center in Turkey of 1646 Elderly Patient...

Med Sci Monit In Press; DOI: 10.12659/MSM.942916  

27 Nov 2023 : Clinical Research  

Evaluating Modified Ultrasound-Guided Serratus Anterior Plane Block for Enhanced Postoperative Recovery in ...

Med Sci Monit In Press; DOI: 10.12659/MSM.942757  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750