Background: Watermelon colon, or rectal vascular ectasia of the colon, is a very rare vascular lesion.
Case Report: A 56-year-old male heavy drinker was admitted to hospital with hematochezia. Colonoscopy revealed linear, watermelon-like vascular stripes throughout the entire colon. Rectal biopsies confirmed the vascular nature of these lesions, showing dilated and trombosed capillaries in the lamina propria. He had neither cirrhosis nor portal hypertension. The watermelon-like lesions regressed spontaneously following the cessation of alcohol intake.
Conclusions: This observation suggests that this condition can be triggered by alcohol.

Keywords: Alcoholism - complications, Capillaries - pathology, Colon - pathology, Colonic Diseases - pathology, Dilatation, Pathologic, Thrombosis - pathology