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29 May 2008

Lipid levels among African and Middle-Eastern Bedouin populations

Jacob DreiherABCDEFG, Arnon D. CohenACDEG, Shimon WeitzmanACDE, Amir SharfABDE, Pesach ShvartzmanADEFG

Med Sci Monit 2008; 14(6): CR339-344 :: ID: 859039

Abstract

Background
Previous studies observed higher high-density lipoprotein (HDL) levels and lower triglycerides levels among people of African ancestry. The goal of this study was to characterize lipid levels in Bedouins of African vs. Middle-Eastern ethnicity.
Material and Method
A cross-sectional study was conducted in a Bedouin primary care clinic in southern Israel, with 4470 listed individuals over the age of 21, of whom 402 (9%) were of African origin. A stratified random sample was included in the analysis. Associations between ethnicity, age, gender and lipid levels were assessed. Multiple linear regression and logistic regression models were used for multivariate analysis.
Results
The study included 261 African Bedouins and 406 Middle-Eastern Bedouins. (median age: 37 years, 58.6% females). The average total cholesterol and low-density lipoprotein (LDL) levels were 10 mg/dl lower among African Bedouins as compared to Middle-Eastern Bedouins (total cholesterol: 168.6 vs. 179.6 mg/dl, p<0.001; LDL: 99.5 vs. 109.0 mg/dl, respectively, p<0.001). Average triglycerides levels were 36 mg/dl lower among African Bedouins as compared to Middle-Eastern Bedouins (102.8 vs. 138.9 mg/dl, respectively, p<0.001). Average HDL levels were 3 mg/dl higher among African Bedouins as compared to Middle-Eastern Bedouins (48.3 vs. 44.6 mg/dl, respectively, p<0.001).
Conclusions
A lower prevalence of dyslipidemia was found in African Bedouins, as compared with Middle-Eastern Bedouins.

Keywords: Multivariate Analysis, Middle East, Lipids - blood, Cholesterol, LDL - blood, Triglycerides - blood, Cholesterol, HDL - blood, Arabs, Africa

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750