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29 January 2009

Acute acalculous cholecystitis with pericholecystitis in a patient with Epstein-Barr Virus infectious mononucleosis

Pavel ChalupaABCDEFG, Miroslav KasparBD, Michal HolubABCDEG

Med Sci Monit 2009; 15(2): CS30-33 :: ID: 869541

Abstract

Background
Acute acalculous cholecystitis is a rare complication of Epstein-Barr virus mononucleosis and involves thickening of the gallbladder wall.
Material and Method
We describe the case of a 22-year-old woman with acute acalculous cholecystitis and pericholecystitis associated with Epstein-Barr virus primary infection. Surgical intervention was not performed, even though gallbladder perforation was suspected. The patient was treated conservatively with careful monitoring, including repeated ultrasonographic examinations.
Results

Conclusions
Epstein-Barr virus infections are usually self-limited, and surgical treatment of acute acalculous cholecystitis should only be considered when the ultrasonographic criteria persist on follow-up examinations or when they deteriorate. This is the first report of a severe course of acute acalculous cholecystitis with suspected gallbladder perforation associated with infectious mononucleosis.

Keywords: Infectious Mononucleosis - virology, Tomography, X-Ray Computed, Gallbladder - ultrasonography, Cholecystitis, Acute - virology, Epstein-Barr Virus Infections - virology, Acalculous Cholecystitis - virology

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750