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31 August 2009

Pneumatosis intestinalis in ulcerative colitis

Ayako MatsumotoBF, Hajime IsomotoACDEF, Saburo ShikuwaABD, Kenta OkamotoB, Naoyuki YamaguchiBC, Ken OhnitaD, Yohei MizutaC, Masahiro FujiiB, Shigeru KohnoDEF

Med Sci Monit 2009; 15(9): CS139-142 :: ID: 878165


UC patients are considered to be at risk for pneumatosis intestinalis (PI).
Material and Method
A 50-year-old man who had been treated with prednisolone for left-sided ulcerative colitis (UC) underwent follow-up colonoscopy. In addition to active colitis in the left colon, some cystic lesions were found in the unaffected ascending colon. Endoscopic ultrasonography and computed tomography confirmed the presence of intramural air, consistent with PI. Since corticosteroid use might contribute to the development of PI, the patient was successfully treated with leukocytapheresis. At the last follow-up colonoscopy the UC was still in remission and the pneumatic cysts were resolving.

It is important to determine the clinical significance of PI in each patient to ensure appropriate therapy.

Keywords: Pneumatosis Cystoides Intestinalis - physiopathology, Leukapheresis, Colitis, Ulcerative - therapy, Anti-Inflammatory Agents - therapeutic use, Prednisolone - therapeutic use

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750