28 April 2010
Combined vasomodulatory therapy for severe pulmonary hypertension in chronic hypersensitivity pneumonitis
Dirk Steffen KoschelABCDEF, Martin KolditzABCD, Gert HoeffkenAD, Michael HalankABCDFMed Sci Monit 2010; 16(5): CS55-57 :: ID: 878528
Abstract
Background
There are only a few reports of pulmonary hypertension (PH) in hypersensitivity pneumonitis (HP) and an approved vasomodulatory therapy for PH does not exist at all for interstitial lung disease (ILD), particularly for HP.
Material and Method
The case of a 53-year-old woman with chronic HP and severe life-threatening PH treated with a combined specific vasomodulatory therapy is reported. Sustained clinical and hemodynamic improvement was achieved.
Results
Conclusions
Further investigation of PH in HP and specific vasomodulatory therapy is necessary.
Keywords: Sulfones - therapeutic use, Pyridazines - therapeutic use, Purines - therapeutic use, Piperazines - therapeutic use, Phenylpropionates - therapeutic use, Iloprost - therapeutic use, Hypertension, Pulmonary - drug therapy, Drug Therapy, Combination, Chronic Disease, Alveolitis, Extrinsic Allergic - complications, Vasodilator Agents - therapeutic use
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