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21 October 2019 : Laboratory Research

Antiproliferative Activity of Carnosic Acid is Mediated via Inhibition of Cell Migration and Invasion, and Suppression of Phosphatidylinositol 3-Kinases (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway

DOI: 10.12659/MSM.917735

Med Sci Monit 2019; 25:7864-7871

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02 Jan 2020 : Laboratory Research

S100A16 Regulates HeLa Cell through the Phosphatidylinositol 3 Kinase (PI3K)/AKT Signaling Pathway

Haibin Zhang, Yongxiu Yang [...]

DOI: 10.12659/MSM.919757

Med Sci Monit 2020; 26:e919757

292 8 68

28 Feb 2020 : Laboratory Research

Synaptotagmin 12 (SYT12) Gene Expression Promotes Cell Proliferation and Progression of Lung Adenocarcinoma and Involves the Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

Kaichao Liu, Jing Luo [...]

DOI: 10.12659/MSM.920351

Med Sci Monit 2020; 26:e920351

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21 Jul 2020 : Laboratory Research

Silencing of Long Non-Coding RNA (LncRNA) Non-Coding RNA Activated by DNA Damage (NORAD) Inhibits Proliferation, Invasion, Migration, and Promotes Apoptosis of Glioma Cells via Downregulating the Expression of AKR1B1

Lun Luo, Chuan Chen [...]

DOI: 10.12659/MSM.922659

Med Sci Monit 2020; 26:e922659

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28 Apr 2020 : Animal Research

Apoptosis Activation in Thyroid Cancer Cells by Jatrorrhizine-Platinum(II) Complex via Downregulation of PI3K/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

KeBin Lu, Wenjun Wei [...]

DOI: 10.12659/MSM.922518

Med Sci Monit 2020; 26:e922518

504 7 15

16 Jun 2019 : Laboratory Research

Formiminotransferase Cyclodeaminase Suppresses Hepatocellular Carcinoma by Modulating Cell Apoptosis, DNA Damage, and Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Pathway

Jiajia Chen, Zemian Chen [...]

DOI: 10.12659/MSM.916202

Med Sci Monit 2019; 25:4474-4484

427 9 44

10 Jun 2019 : Laboratory Research

microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract

Yan Liu, Huanhuan Li [...]

DOI: 10.12659/MSM.916881

Med Sci Monit 2019; 25:4314-4321

272 2 55

05 Aug 2019 : Laboratory Research

Salidroside Suppresses IL-1β-Induced Apoptosis in Chondrocytes via Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Inhibition

Mingzheng Wu, Rui Hu [...]

DOI: 10.12659/MSM.917851

Med Sci Monit 2019; 25:5833-5840

326 8 23

25 Mar 2019 : Clinical Research

Neuro-Protective Role of Metformin in Patients with Acute Stroke and Type 2 Diabetes Mellitus via AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Pathway and Oxidative Stress

Min Zhao, Xiao Wan Li [...]

DOI: 10.12659/MSM.911250

Med Sci Monit 2019; 25:2186-2194

1324 16 19

02 Oct 2019 : Clinical Research

Tivantinib Hampers the Proliferation of Glioblastoma Cells via PI3K/Akt/Mammalian Target of Rapamycin (mTOR) Signaling

Yukun Wu, Zhizhang Li [...]

DOI: 10.12659/MSM.919319

Med Sci Monit 2019; 25:7383-7390

313 4 26

01 Jan 2019 : Laboratory Research

Rho GTPase Activating Protein 24 (ARHGAP24) Silencing Promotes Lung Cancer Cell Migration and Invasion by Activating β-Catenin Signaling

Lei Wang, Saie Shen [...]

DOI: 10.12659/MSM.911503

Med Sci Monit 2019; 25:21-31

355 5 42

17 Feb 2019 : Laboratory Research

Phosphatase Actin Regulator-1 (PHACTR-1) Knockdown Suppresses Cell Proliferation and Migration and Promotes Cell Apoptosis in the bEnd.3 Mouse Brain Capillary Endothelial Cell Line

Yao Jing, Lin Zhang [...]

DOI: 10.12659/MSM.912586

Med Sci Monit 2019; 25:1291-1300

382 7 100

03 Jan 2019 : Laboratory Research

Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway

Lin Chen, Guangsheng Yang [...]

DOI: 10.12659/MSM.912929

Med Sci Monit 2019; 25:77-86

395 18 18

17 Mar 2019 : Laboratory Research

Murrayanine Induces Cell Cycle Arrest, Oxidative Stress, and Inhibition of Phosphorylated p38 Expression in A549 Lung Adenocarcinoma Cells

Jingbao Zhang, Yanfei Gao [...]

DOI: 10.12659/MSM.913873

Med Sci Monit 2019; 25:2002-2008

188 0 53

04 Jun 2019 : Animal Research

Loganin Attenuates Osteoarthritis in Rats by Inhibiting IL-1β-Induced Catabolism and Apoptosis in Chondrocytes Via Regulation of Phosphatidylinositol 3-Kinases (PI3K)/Akt

Yi Yang, Yuntao Gu [...]

DOI: 10.12659/MSM.915064

Med Sci Monit 2019; 25:4159-4168

361 10 62

19 Jun 2019 : Clinical Research

Proliferation of Ovarian Granulosa Cells in Polycystic Ovarian Syndrome Is Regulated by MicroRNA-24 by Targeting Wingless-Type Family Member 2B (WNT2B)

Zhong Yuanyuan, Wang Zeqin [...]

DOI: 10.12659/MSM.915320

Med Sci Monit 2019; 25:4553-4559

360 3 30

08 Jul 2019 : Laboratory Research

Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells in Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway

Chao Li, Yuqiu Zhou [...]

DOI: 10.12659/MSM.915387

Med Sci Monit 2019; 25:5054-5061

237 0 41

08 Jun 2019 : Laboratory Research

Knockdown of Hypoxia-Inducible Factor 1α (HIF-1α) Promotes Autophagy and Inhibits Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Ovarian Cancer Cells

Jinling Huang, Likun Gao [...]

DOI: 10.12659/MSM.915730

Med Sci Monit 2019; 25:4250-4263

455 8 43

28 Aug 2019 : Animal Research

High-Mobility Group Box 1 (HMGB1) Induces Migration of Endothelial Progenitor Cell via Receptor for Advanced Glycation End-Products (RAGE)-Dependent PI3K/Akt/eNOS Signaling Pathway

Yulong Zhang, Bo You [...]

DOI: 10.12659/MSM.915829

Med Sci Monit 2019; 25:6462-6473

496 5 25

05 Sep 2018 : Laboratory Research

Calycosin, a Phytoestrogen Isoflavone, Induces Apoptosis of Estrogen Receptor-Positive MG-63 Osteosarcoma Cells via the Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

Haitao Sun, Mengfan Yin [...]

DOI: 10.12659/MSM.910201

Med Sci Monit 2018; 24: LBR6178-6186

373 2 45

12 Jun 2018 : Laboratory Research

Role of Hydroxysteroid Dehydrogenase-Like 2 (HSDL2) in Human Ovarian Cancer

Qing Sun, Yilin Zhang [...]

DOI: 10.12659/MSM.909418

Med Sci Monit 2018; 24: LBR3997-4008

334 2 79

10 Apr 2018 : Laboratory Research

Baicalin, a Chinese Herbal Medicine, Inhibits the Proliferation and Migration of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells, A549 and H1299, by Activating the SIRT1/AMPK Signaling Pathway

Jiawen You, Jun Cheng [...]

DOI: 10.12659/MSM.909627

Med Sci Monit 2018; 24: LBR2126-2133

471 6 54

18 Mar 2018 : Animal Research

Recombinant Osteopontin Improves Neurological Functional Recovery and Protects Against Apoptosis via PI3K/Akt/GSK-3β Pathway Following Intracerebral Hemorrhage

Wenqian Zhang, Ying Cui [...]

DOI: 10.12659/MSM.905700

Med Sci Monit 2018; 24: ANS1588-1596

342 4 32

05 Feb 2018 : Laboratory Research

lncRNA BG981369 Inhibits Cell Proliferation, Migration, and Invasion, and Promotes Cell Apoptosis by SRY-Related High-Mobility Group Box 4 (SOX4) Signaling Pathway in Human Gastric Cancer

Xiuli Dong, Renpin Chen [...]

DOI: 10.12659/MSM.905965

Med Sci Monit 2018; 24: MOL718-726

280 2 82

31 Jan 2018 : Laboratory Research

Expression and Comparison of Cbl-b in Lung Squamous Cell Carcinoma and Adenocarcinoma

Peng Li, Hongliang Liu [...]

DOI: 10.12659/MSM.908076

Med Sci Monit 2018; 24: LBR623-635

273 1 27

21 Nov 2018 : Laboratory Research

miR-339-5p Increases Radiosensitivity of Lung Cancer Cells by Targeting Phosphatases of Regenerating Liver-1 (PRL-1)

Jia Wang, Mawei Jiang [...]

DOI: 10.12659/MSM.910808

Med Sci Monit 2018; 24: LBR8408-8416

264 5 25

12 Oct 2018 : Laboratory Research

Anticancer Activity of Mukonal Against Human Laryngeal Cancer Cells Involves Apoptosis, Cell Cycle Arrest, and Inhibition of PI3K/AKT and MEK/ERK Signalling Pathways

Liu Li, Lu Huizhi [...]

DOI: 10.12659/MSM.910702

Med Sci Monit 2018; 24: LBR7295-7302

249 3 35

07 Oct 2018 : Laboratory Research

Gambogic Acid Induces Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells by Suppressing Notch Signaling

Minghua Zhu, Minjie Wang [...]

DOI: 10.12659/MSM.912563

Med Sci Monit 2018; 24: LBR7146-7151

331 4 57

19 Sep 2018 : Animal Research

Protective Effects of Oleuropein Against Cerebral Ischemia/Reperfusion by Inhibiting Neuronal Apoptosis

Weijing Zhang, Xiaogang Liu [...]

DOI: 10.12659/MSM.912336

Med Sci Monit 2018; 24: ANS6587-6598

254 3 14

11 Feb 2018 : Laboratory Research

Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway

Er-Min Wang, Qiu-Ling Fan [...]

DOI: 10.12659/MSM.907814

Med Sci Monit 2018; 24: LBR846-854

263 3 14

18 Sep 2018 : Laboratory Research

Anticancer Activity of Phloretin Against Human Gastric Cancer Cell Lines Involves Apoptosis, Cell Cycle Arrest, and Inhibition of Cell Invasion and JNK Signalling Pathway

Min Xu, Weiguang Gu [...]

DOI: 10.12659/MSM.910542

Med Sci Monit 2018; 24: LBR6551-6558

297 7 30

09 Sep 2018 : Laboratory Research

Marsdenia Tenacissima Extract Inhibits Proliferation and Promotes Apoptosis in Human Ovarian Cancer Cells

Yuhong Zhang, Yangjia Zhang

DOI: 10.12659/MSM.909726

Med Sci Monit 2018; 24: LBR6289-6297

294 14 52

27 Aug 2018 : Clinical Research

MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2)

Na Li, Mei Han [...]

DOI: 10.12659/MSM.909458

Med Sci Monit 2018; 24: CLR5960-5972

301 3 18

16 Jul 2018 : Laboratory Research

The Effects of Ludartin on Cell Proliferation, Cell Migration, Cell Cycle Arrest and Apoptosis Are Associated with Upregulation of p21WAF1 in Saos-2 Osteosarcoma Cells In Vitro

Shuang-li Zhang, Bao-lin Li [...]

DOI: 10.12659/MSM.909193

Med Sci Monit 2018; 24: LBR4926-4933

233 0 21

14 Feb 2017 : Animal Research

Evaluating the Effectiveness of GTM-1, Rapamycin, and Carbamazepine on Autophagy and Alzheimer Disease

Lijuan Zhang, Lina Wang [...]

DOI: 10.12659/MSM.898679

Med Sci Monit 2017; 23:801-808

319 3 39

Editorial

01 July 2022 : Editorial  

Editorial: World Health Organization (WHO) Variants of Concern Lineages Under Monitoring (VOC-LUM) in Response to the Global Spread of Lineages and Sublineages of Omicron, or B.1.1.529, SARS-CoV-2

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.937676

Med Sci Monit 2022; 28:e937676

SARS-CoV-2/COVID-19

27 June 2022 : Clinical Research  

Shoulder Injury Related to Vaccine Administration (SIRVA) in 16 Patients Following COVID-19 Vaccination Who...

Med Sci Monit In Press; DOI: 10.12659/MSM.937430  

27 May 2022 : Clinical Research  

Factors Associated with Falls During Hospitalization for Coronavirus Disease 2019 (COVID-19)

Med Sci Monit 2022; 28:e936547

In Press

01 Jul 2022 : Clinical Research  

Does Early-Period Patient Dissatisfaction Turn Into Satisfaction Over Time After Total Knee Replacement?

Med Sci Monit In Press; DOI: 10.12659/MSM.936792  

30 Jun 2022 : Laboratory Research  

Bcl-2 19-kDa Interacting Protein 3 (BNIP3)-Mediated Mitophagy Attenuates Intermittent Hypoxia-Induced Human...

Med Sci Monit In Press; DOI: 10.12659/MSM.936760  

30 Jun 2022 : Clinical Research  

Antioxidant System and Ions Concentrations After Femoral Neck and Resurfacing Hip Arthroplasty

Med Sci Monit In Press; DOI: 10.12659/MSM.936335  

28 Jun 2022 : Meta-Analysis  

Urodynamics in Early Diagnosis of Diabetic Bladder Dysfunction in Women: A Systematic Review and Meta-Analysis

Med Sci Monit In Press; DOI: 10.12659/MSM.937166  

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30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

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08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

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01 Nov 2020 : Review article  

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01 Jan 2022 : Editorial  

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Med Sci Monit 2022; 28:e935952

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750